Upcoming Events

Scottish Radiological Society Spring Meeting 2019 May 17, 2019 09:00 AM - 05:00 PM — McDiarmid Park, Perth
Pint of Science: The Hidden World of Imaging May 20, 2019 07:00 PM - 10:00 PM — Brutti Compadres, 3 Viginia Court, Glasgow
Pint of Science: The Beautiful Mind May 22, 2019 07:30 PM - 10:30 PM — Curly Coo, 51 Barnton Street, Stirling
Scottish Clinical Imaging Network (SCIN) Annual Event 2019 May 23, 2019 09:00 AM - 04:00 PM — COSLA, Verity House, 19 Haymarket Yards, Edinburgh
2019 SINAPSE ASM Jun 21, 2019 09:30 AM - 05:00 PM — Apex City Quay Hotel, Dundee

SINAPSE Image of the Month: TSPO PET Radiotracer

April 2018 SINAPSE Image of the Month

Courtesy of Dr Adriana Tavares, this image shows PET signal measured in heart using a new radiotracer for imaging cardiovascular inflammation. Targeting the 18 kDa translocator protein (TSPO), this is the first fluorinated TSPO PET radiotracer with binding to human tissue independent from the rs6971 genetic polymorphism.

This collaborative work (Universities of Edinburgh and Glasgow) is currently at the radiotracer preclinical validation stage with aim of translating to humans, and has recently received funding support from the British Heart Foundation.

An important property of the new TSPO PET radiotracer is its selectivity for imaging inflammation, as shown below: the signal measured in heart is reduced from before (left) to after (right) administration of PK11195, a selective TSPO drug.