Upcoming Events

ISMRM Workshop on MR Value Mar 11, 2019 - Mar 13, 2019 — University of Edinburgh
European Molecular Imaging Meeting 2019 Mar 19, 2019 - Mar 22, 2019 — Scottish Event Campus, Glasgow
2nd International Conference on Medical Imaging with Deep Learning Jul 08, 2019 - Jul 10, 2019 — ICL South Kensington Campus, London
4th International Workshop on Image Processing Techniques and Applications Jul 22, 2019 - Jul 23, 2019 — Centre for Mathematical Imaging Techniques (CMIT), University of Liverpool, England
Medical Image Understanding and Analysis Conference 2019 Jul 24, 2019 - Jul 26, 2019 — University of Liverpool, England

SINAPSE Image of the Month: TSPO PET Radiotracer

April 2018 SINAPSE Image of the Month

Courtesy of Dr Adriana Tavares, this image shows PET signal measured in heart using a new radiotracer for imaging cardiovascular inflammation. Targeting the 18 kDa translocator protein (TSPO), this is the first fluorinated TSPO PET radiotracer with binding to human tissue independent from the rs6971 genetic polymorphism.

This collaborative work (Universities of Edinburgh and Glasgow) is currently at the radiotracer preclinical validation stage with aim of translating to humans, and has recently received funding support from the British Heart Foundation.

An important property of the new TSPO PET radiotracer is its selectivity for imaging inflammation, as shown below: the signal measured in heart is reduced from before (left) to after (right) administration of PK11195, a selective TSPO drug.