Upcoming Events

Edinburgh Imaging PhD Expo 2018 Oct 18, 2018 01:30 PM - 06:00 PM — Room G07, Informatics Building, University of Edinburgh
PET is Wonderful Annual Meeting 2018 Oct 29, 2018 09:00 AM - 05:00 PM — South Hall Complex, Pollock Halls, University of Edinburgh
8th SINAPSE Neuro-oncology Meeting Oct 30, 2018 09:30 AM - 04:00 PM — Royal College of Physicians and Surgeons of Glasgow, 232-242 St Vincent Street, Glasgow
7th Annual Scottish Radiotherapy Research Forum Nov 01, 2018 10:00 AM - 04:30 PM — Stirling Court Hotel, University of Stirling
Scottish Radiological Society Annual General Meeting 2018 Nov 02, 2018 12:00 AM — President’s Suite, BT Murrayfield Stadium, Edinburgh

SINAPSE Image of the Month: TSPO PET Radiotracer

April 2018 SINAPSE Image of the Month

Courtesy of Dr Adriana Tavares, this image shows PET signal measured in heart using a new radiotracer for imaging cardiovascular inflammation. Targeting the 18 kDa translocator protein (TSPO), this is the first fluorinated TSPO PET radiotracer with binding to human tissue independent from the rs6971 genetic polymorphism.

This collaborative work (Universities of Edinburgh and Glasgow) is currently at the radiotracer preclinical validation stage with aim of translating to humans, and has recently received funding support from the British Heart Foundation.

An important property of the new TSPO PET radiotracer is its selectivity for imaging inflammation, as shown below: the signal measured in heart is reduced from before (left) to after (right) administration of PK11195, a selective TSPO drug.