Upcoming Events

Molecular Imaging Workshop 2017 Nov 20, 2017 - Nov 23, 2017 — San Sebastian, Spain
TOPIM ("hot TOPics in IMaging") 2018: Imaging Metabolism Jan 21, 2018 - Jan 26, 2018 — L'Ecole de Physique des Houches, France
SINAPSE Molecular Imaging PET/SPECT focus group meeting Feb 05, 2018 10:30 AM - 04:00 PM — Carnegie Lecture Theatre (C3-05), Joseph Black Building, School of Chemistry, University of Glasgow
'Let's Talk About Health' free public lecture Feb 21, 2018 05:30 PM - 06:30 PM — Wellcome Auditorium, Queen’s Medical Research Institute, University of Edinburgh

PECRE award recipients

October 2017 - Five SINAPSE members awarded funding for international research exchanges

Congratulations to the SINAPSE early career researchers selected to receive PECRE funding for international research exchanges in the latest round of applications:

 


Donald Lyall

Donald Lyall is a lecturer in Public Health at the University of Glasgow. He received his PhD in 2013 from the University of Edinburgh, supervised by Profs David Porteous, Ian Deary and Joanna Wardlaw. His work [Google Scholar account here] focuses on genetic contributions to brain ageing: specifically the apolipoprotein E4 (APOE) genotype, which is a common risk factor for Alzheimer’s disease.

Donald will spend a month at the Neurogenetics section of Pfizer in Boston (USA), focusing on resting state functional, and diffusion tensor MRI processing methods as applied to neurogenetics, to return to Scotland and apply this understanding to the UK Biobank brain imaging data. He is working on this as part of the (UoG) Institute of Health and Wellbeing UK Biobank research team.

 

Laura Pidgeon

Laura Pidgeon studied Psychology at the University of Glasgow before completing her MSc and PhD in cognitive ageing and brain imaging at the Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh. She is now a Research Associate in Mental Health and Wellbeing at the University of Glasgow. Her research examines the cognitive and structural and functional brain changes associated with mood disorders.

For her PECRE exchange visit, Laura will visit Dr Francesco Benedetti’s Psychiatry and Clinical Psychobiology group at the San Raffaele Hospital in Milan (Italy), where she will learn about their work on the influence of circadian rhythmicity genes on white matter integrity in bipolar disorder. She will then visit the Kimel Family Imaging-Genetics Lab at the Centre for Addiction and Mental Health in Toronto (Canada) where she will learn about the techniques used to study the influence of genetic variants associated with psychiatric disorders on brain structure.



Shaun Stone

Shaun Stone is in the second year of his PhD studentship in Medical Imaging at the University of Aberdeen, funded by SINAPSE and IXICO. He completed his undergraduate (BSc) degree in Psychology with Neuroscience, and postgraduate (MSc) degree in Neuroimaging, at Bangor University, North Wales – where he gained experience using a range of neuroimaging techniques. Shaun continues to learn, using his neuro-background to transfer into computational medicine and diagnostic imaging.

During his PECRE exchange visit at the IDEA (Image Design Enhancement Analysis) lab at the University of North Carolina (USA), Shaun will work with brain imaging data and longitudinal records of cognition of the participants in the Scottish cohorts – Aberdeen Children of the Nineteen Fifties (ACONF) and Stratifying Resilience and Depression Longitudinally (STRADL). He will seek to replicate existing work by the IDEA group that accurately estimates intelligence quotient (IQ) using brain morphometrics, and validate the IQ-estimation techniques on the ACONF-STRADL cohort. Secondly, he will train a machine learning model to estimate a proxy of cognitive reserve - the unexplained variance between neuropathology and cognition - using brain imaging variables. Providing such models are accurate in predicting patient pathology, these approaches will be extremely useful for both clinical/pharmaceutical trials and for earlier diagnosis of patients with dementia – improving the accuracy of diagnosis and more importantly earlier diagnosis for more appropriate intervention and care.

 

Michael Stringer

Michael Stringer is a Research Fellow in Magnetic Resonance Imaging and Image Analysis at the University of Edinburgh in the small vessel disease (SVD) group led by Prof Joanna Wardlaw. He is currently involved with a number of studies involving SVD, in particular the multicentre H2020 SVDs@Target and Leducq Transatlantic Network of Excellence investigating the role of perivascular spaces in cerebral SVD, as well as the UK Dementia Research Institute at the University of Edinburgh. He previously completed his PhD in the Aberdeen Biomedical Imaging Centre at the University of Aberdeen.

Michael's current research interests focus on the development and application of advanced MRI techniques to explore different aspects of small vessel disease, including cerebrovascular reactivity, BBB permeability and magnetic resonance spectroscopy. For his PECRE exchange, Michael will visit three other groups involved with the Leducq Transatlantic Network all of which are leading centres for research into small vessel disease, namely the Zilkha Neurogenetic Institute of the University of Southern California (USA), Yale University (USA) and Sunnybrook Health Sciences Centre (Canada). The visits will provide opportunities to learn about advanced scanning and analysis techniques as well as assisting with harmonisation for on-going work. A significant feature of the Leducq Transatlantic Network is the involvement of experts in clinical and preclinical imaging, therefore a central aim will be to consider ways of improving the translatability and relevance of findings from rodent models to humans and vice versa.

 

Kanheng Zhou

Kanheng Zhou is a third year PhD student in Biomedical Engineering at the University of Dundee under the supervision of Prof Zhihong Huang. His research project is mainly focused on the methodology development of elasticity evaluation of biological soft tissue by using focused ultrasound and high-resolution phase-sensitive optical coherence tomography (OCT) system, for disease diagnosis and treatment monitoring purposes.

During his PECRE exchange visit to Biophotonics and Imaging Laboratory at the University of Washington (USA) with Prof Ruikang Wang, Kanheng plans to explore ex-vivo and in-vivo methodology for high resolution viscosity compensated elastography on different biological soft tissues, by taking advantage of access to the ultra-high spatial resolution swept source OCT system and small animal models there.