CAFACHEM 2020 Summer School on Organic & Halogen Radiochemistry Aug 26, 2020 - Aug 28, 2020 — Virtual Meeting (online)
Scottish Dementia Research Consortium Annual Conference 2020 [rescheduled] Sep 07, 2020 10:00 AM - 02:30 PM — Virtual Meeting (online)
Society for Magnetic Resonance Angiography - SMRA2020 VIRTUAL Sep 11, 2020 - Sep 13, 2020 — Virtual Meeting (online)
Ophthalmic Medical Image Analysis MICCAI 2020 Workshop Oct 08, 2020 12:00 AM — Virtual Meeting (online)

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

SINAPSE Image of the Month: MRI functional connectivity

December 2018 SINAPSE Image of the Month

December2018

Courtesy of Dr Neil Basu, this image shows the result from functional connectivity analysis of fMRI data in rheumatoid arthritis (RA) patients. RA is a chronic inflammatory disorder in which pain symptoms are often reported even after peripheral inflammation is controlled with anti-inflammatory treatment. Such pain not originating from inflammation may instead have its origin in dysfunctional central nervous system pain processing, characteristic of the primary chronic pain syndrome of fibromyalgia (FM). Phenotypic features of FM, including reported pain and disability, can be measured with a continuous scale of ‘FMness’ even among RA patients not fully satisfying the FM criteria.

RA patients underwent fMRI brain scanning while performing a continuous cognitive task, and functional connectivity analysis was subsequently performed to examine temporal correlations in the BOLD signal between networks of interest and other regions across the whole brain. Increased functional connectivity between the default mode network [left] and the left mid/posterior insula [right] was found for RA patients reporting higher levels of FMness. DMN–insular cortex hyperconnectivity has been previously reported in fMRI studies with FM patients; many cognitive neuroimaging studies have implicated the DMN in self‐referential mental activity and the insula in multimodal sensory processing. The finding of this neurobiologic feature in RA patients who have increased levels of FMness indicates that centralized pain pathways coexist with inflammation-driven pathways in RA, and suggests that such patients’ pain symptoms may respond to centrally acting therapies which are effective for FM, instead of or in addition to anti-inflammatory therapies.

 

The image is taken from a recent study published in Arthritis & Rheumatology, where it appeared on the journal cover:

Basu N, Kaplan CM, Ichesco E, Larkin T, Harris RE, Murray A, Waiter G, Clauw, DJ. Neurobiologic Features of Fibromyalgia Are Also Present Among Rheumatoid Arthritis Patients. Arthritis Rheumatol 2018; 70:1000-1007.