Upcoming Events

Digital Health Product Forge Feb 21, 2019 - Feb 24, 2019 — The Crags Centre, 10 Bowmont Place, Edinburgh
Professor James Boardman inaugural lecture Feb 25, 2019 05:30 PM - 06:30 PM — Lecture Theatre A, Chancellor's Building, Edinburgh, EH16 4SB
ISMRM Workshop on MR Value Mar 11, 2019 - Mar 13, 2019 — University of Edinburgh
Scotland's New Industrial Centre for AI Research in Digital Diagnostics: Vision & Opportunities in Grampian Mar 11, 2019 06:00 PM - 08:00 PM — The Rowett Institute, Ashgrove Road West, Aberdeen
Scotlands New Industrial Centre for AI Research in Digital Diagnostics: Vision & Opportunities in Glasgow Mar 14, 2019 11:30 AM - 01:30 PM — Teaching and Learning Centre, Queen Elizabeth University Hospital Glasgow

SINAPSE Image of the Month: Retinal vascular parameters

May 2018 SINAPSE Image of the Month

Courtesy of Dr Tom MacGillivray, this image of the retina was acquired with an ultra-widefield (UWF) scanning laser ophthalmoscope (Optos P200C AF). UWF technology allows the entire retina to be imaged, including the periphery. Software developed by SINAPSE researchers in the Vascular Assessment and Measurement Platform for Images of the REtina (VAMPIRE) project measures the following retinal vascular parameters for grading: the complexity of the vascular branching pattern [turquoise lines], branching points [green dots], and vessel widths for arterioles [red line] and venules [blue line]. Such vascular characteristics quantifiable on retinal imaging have been shown to reflect cerebrovascular health, complementing brain imaging.

A recently published pilot study in collaboration with VAMPIRE and researchers at Queen's University Belfast identified retinal vascular parameters analysed from UWF images as potential biomarkers for Alzheimer’s disease and its progression:

Csincsik L, MacGillivray TJ, Flynn E, Pellegrini  E, Papanastasiou G, Barzegar-Befroei N, Csutak A, Bird AC, Ritchie CW, Peto T, Lengyel I. Peripheral Retinal Imaging Biomarkers for Alzheimer’s Disease: A Pilot Study. Ophthalmic Res 2018; 59:182-192.