Upcoming Events

Society for Magnetic Resonance Angiography 30th Annual International Conference Aug 29, 2018 - Aug 31, 2018 — University of Glasgow
Future of Minimally Invasive Endoscopy Workshop Sep 05, 2018 09:30 AM - 04:30 PM — thestudio, 67 Hope Street, Glasgow
British Association for Cognitive Neuroscience Meeting 2018 Sep 06, 2018 - Sep 07, 2018 — University of Glasgow
Predictive Intelligence in Medicine MICCAI 2018 Workshop Sep 16, 2018 12:00 AM — Granada, Spain
Scottish Molecular Imaging Meeting 2018 Sep 19, 2018 09:00 AM - 07:00 PM — Beatson Institute for Cancer Research (BICR), Glasgow

SINAPSE Image of the Month: TSPO PET Radiotracer

April 2018 SINAPSE Image of the Month

Courtesy of Dr Adriana Tavares, this image shows PET signal measured in heart using a new radiotracer for imaging cardiovascular inflammation. Targeting the 18 kDa translocator protein (TSPO), this is the first fluorinated TSPO PET radiotracer with binding to human tissue independent from the rs6971 genetic polymorphism.

This collaborative work (Universities of Edinburgh and Glasgow) is currently at the radiotracer preclinical validation stage with aim of translating to humans, and has recently received funding support from the British Heart Foundation.

An important property of the new TSPO PET radiotracer is its selectivity for imaging inflammation, as shown below: the signal measured in heart is reduced from before (left) to after (right) administration of PK11195, a selective TSPO drug.