4th International Conference on Medical Imaging with Deep Learning Jul 07, 2021 - Jul 09, 2021 — Virtual Meeting (online)
Medical Image Understanding and Analysis Conference 2021 Jul 12, 2021 - Jul 14, 2021 — Virtual Meeting (online)
Medical Imaging Convention [rescheduled] Sep 15, 2021 - Sep 16, 2021 — National Exhibition Centre, Birmingham, England
2021 SINAPSE ASM Sep 16, 2021 - Sep 17, 2021 — Technology & Innovation Centre, University of Strathclyde, 99 George Street, Glasgow
Total Body PET 2021 conference [rescheduled] Sep 22, 2021 - Sep 24, 2021 — Virtual Meeting (online)

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Elizabeth Jameson

Position: SINAPSE PhD Student
Institute:
Department:


Description of Phd:

 

The focus of this project will be to develop a one-step labelling procedure suitable for the rapid and efficient labelling of a variety of probes with 18F fluoride or 68Ga. The key steps of all the proposed approaches will be:  (a). The generation of labelled material via a variety of PET-isotope mediated cleavage processes, giving rise to highly pure and concentrated samples. (b). The probes can be peptides thus allowing the approach to be applicable generically while the pre-probes can be made en masse and cleaved just when required (c). The liberation will be rapid and carried out in a flow manner. Three routes will be explored:  (i). The desired peptide pre-probe will be synthesised by solid phase methods, conjugated to a boronate carboxylic acid and then cleaved and purified. This will subsequently be captured onto a catechol derivatised resin. Treatment of the captured probe  (ideally a macroporous PS) with the fluoride source will cleave the probe off the support and give the stable boron fluoride label.1,2 (ii). The desired peptide pre-probe will be conjugated to an azido group, purified and captured onto a sulfonyl chloride resin that has been derivatised with an propargyl alcohol, using a Cu(I) catalysed [3+2] cycloaddition5. Treatment with the fluoride source will again cleave the probe off the support. (iii). As above the peptide will be synthesised, purified and then immobilised back on to a solid support. In this case the Ga(III) will induce co-ordination followed by resin mediated ester cleavage to give the desired liganded complex in solution.