Upcoming Events

ISMRM Workshop on MR Value Mar 11, 2019 - Mar 13, 2019 — University of Edinburgh
European Molecular Imaging Meeting 2019 Mar 19, 2019 - Mar 22, 2019 — Scottish Event Campus, Glasgow
Edinburgh SPM Course 2019 Apr 01, 2019 - Apr 05, 2019 — University of Edinburgh
RiiSE19 Conference Apr 13, 2019 12:00 AM — Central Edinburgh
Scottish Radiological Society Spring Meeting 2019 May 17, 2019 09:00 AM - 05:00 PM — McDiarmid Park, Perth

Olivia Hamilton

Home page: Go to homepage
Position: PhD Student - Wellcome Trust 4-year PhD in Translational Neuroscience

Interests:

I am interested in the vulnerability of the ageing brain, especially changes cognitive ability and behaviour that can occur as part of 'healthy' ageing, or as a result of diseases such as stroke or dementia.

My PhD project focuses on changes in cognitive ability in cerebral small vessel disease and how this might relate to structural brain changes that occur throughout the disease course.

Currently, I am conducting a systematic review on the associations between domain specific cognitive ability and structural brain changes (visible on MRI) in sporadic small vessel disease (https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=80215). I am also employing structural equation modelling techniques to investigate the relationship between visible MRI markers of sporadic small vessel disease and cognitive ability longitudinally in several large cohorts.

My research aims to better characterise the cognitive symptomatology of cerebral small vessel disease and its trajectory over the disease course; examine how this relates to underlying changes in brain structure; and to explore how we can use neuroimaging, psychological and epidemiological data to more accurately predict outcomes for people with cerebral small vessel disease.

Supervisors: Professor Joanna Wardlaw and Professor Ian Deary

Institute: University of Edinburgh

Department: Centre for Clinical Brain Sciences


Key Publications

Hamilton et al. An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort 1936. doi: https://doi.org/10.1101/278234

Penny Rapaport, Gill Livingston, Olivia Hamilton, Rebecca Turner,Aisling Stringer, Sarah Robertson, Claudia Cooper. 2018. How do care home staff understand, manage and respond to agitation in people with dementia? A qualitative study. BMJ Open, 8(6)

Robertson, S., Cooper, C., Hoe, J., Hamilton, O., Stringer, A. and Livingston, G. 2017. Proxy rated quality of life of care home residents with dementia: a systematic review. International Psychogeriatrics, 29(4): 569-581.