Upcoming Events

PET is Wonderful Annual Meeting 2018 Oct 29, 2018 09:00 AM - 05:00 PM — South Hall Complex, Pollock Halls, University of Edinburgh
2018 NHS Research Scotland Annual Conference Oct 30, 2018 09:00 AM - 05:00 PM — Perth Concert Hall
8th SINAPSE Neuro-oncology Meeting Oct 30, 2018 09:30 AM - 04:00 PM — Royal College of Physicians and Surgeons of Glasgow, 232-242 St Vincent Street, Glasgow
Image Guided Therapies Network+ Tri-Annual Meeting Nov 01, 2018 10:00 AM - 05:00 PM — Wolfson Lecture Theatre, Ninewells Hospital, Dundee
7th Annual Scottish Radiotherapy Research Forum Nov 01, 2018 10:00 AM - 04:30 PM — Stirling Court Hotel, University of Stirling

Olivia Hamilton

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Position: PhD Student - Wellcome Trust 4-year PhD in Translational Neuroscience

Interests:

I am interested in the vulnerability of the ageing brain, especially changes cognitive ability and behaviour that can occur as part of 'healthy' ageing, or as a result of diseases such as stroke or dementia.

My PhD project focuses on changes in cognitive ability in cerebral small vessel disease and how this might relate to structural brain changes that occur throughout the disease course.

Currently, I am conducting a systematic review on the associations between domain specific cognitive ability and structural brain changes (visible on MRI) in sporadic small vessel disease (https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=80215). I am also employing structural equation modelling techniques to investigate the relationship between visible MRI markers of sporadic small vessel disease and cognitive ability longitudinally in several large cohorts.

My research aims to better characterise the cognitive symptomatology of cerebral small vessel disease and its trajectory over the disease course; examine how this relates to underlying changes in brain structure; and to explore how we can use neuroimaging, psychological and epidemiological data to more accurately predict outcomes for people with cerebral small vessel disease.

Supervisors: Professor Joanna Wardlaw and Professor Ian Deary

Institute: University of Edinburgh

Department: Centre for Clinical Brain Sciences


Key Publications

Hamilton et al. An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort 1936. doi: https://doi.org/10.1101/278234

Penny Rapaport, Gill Livingston, Olivia Hamilton, Rebecca Turner,Aisling Stringer, Sarah Robertson, Claudia Cooper. 2018. How do care home staff understand, manage and respond to agitation in people with dementia? A qualitative study. BMJ Open, 8(6)

Robertson, S., Cooper, C., Hoe, J., Hamilton, O., Stringer, A. and Livingston, G. 2017. Proxy rated quality of life of care home residents with dementia: a systematic review. International Psychogeriatrics, 29(4): 569-581.