Upcoming Events

PET is Wonderful Annual Meeting 2018 Oct 29, 2018 09:00 AM - 05:00 PM — South Hall Complex, Pollock Halls, University of Edinburgh
2018 NHS Research Scotland Annual Conference Oct 30, 2018 09:00 AM - 05:00 PM — Perth Concert Hall
8th SINAPSE Neuro-oncology Meeting Oct 30, 2018 09:30 AM - 04:00 PM — Royal College of Physicians and Surgeons of Glasgow, 232-242 St Vincent Street, Glasgow
Image Guided Therapies Network+ Tri-Annual Meeting Nov 01, 2018 10:00 AM - 05:00 PM — Wolfson Lecture Theatre, Ninewells Hospital, Dundee
7th Annual Scottish Radiotherapy Research Forum Nov 01, 2018 10:00 AM - 04:30 PM — Stirling Court Hotel, University of Stirling

SINAPSE Image of the Month: Retinal vascular parameters

May 2018 SINAPSE Image of the Month

Courtesy of Dr Tom MacGillivray, this image of the retina was acquired with an ultra-widefield (UWF) scanning laser ophthalmoscope (Optos P200C AF). UWF technology allows the entire retina to be imaged, including the periphery. Software developed by SINAPSE researchers in the Vascular Assessment and Measurement Platform for Images of the REtina (VAMPIRE) project measures the following retinal vascular parameters for grading: the complexity of the vascular branching pattern [turquoise lines], branching points [green dots], and vessel widths for arterioles [red line] and venules [blue line]. Such vascular characteristics quantifiable on retinal imaging have been shown to reflect cerebrovascular health, complementing brain imaging.

A recently published pilot study in collaboration with VAMPIRE and researchers at Queen's University Belfast identified retinal vascular parameters analysed from UWF images as potential biomarkers for Alzheimer’s disease and its progression:

Csincsik L, MacGillivray TJ, Flynn E, Pellegrini  E, Papanastasiou G, Barzegar-Befroei N, Csutak A, Bird AC, Ritchie CW, Peto T, Lengyel I. Peripheral Retinal Imaging Biomarkers for Alzheimer’s Disease: A Pilot Study. Ophthalmic Res 2018; 59:182-192.