People

Computational cardiovascular mechanics

The aim of my research is to generate new scientific knowledge and methods using innovative ideas in numerical methods and biomechanics that contribute towards improved cardiovascular healthcare.

I have worked as a physicist on a range of imaging projects involving SPECT,PET, CT and MRI. I am lead MRI pulse sequence developer in Aberdeen. More recently I have been working in image segmentation and pharmacokinetic modelling.

Pulmonary/pleural imaging with focus on pharmacokinetics, radiomics and imaging biomarkers. Venous thromboembolic disease. Whole body MRI imaging.

Computed Tomography (small animal, exotics, equine)

Contrast Enhanced Ultrasound (small animal)

Abdominal and Thoracic Ultrasound (small animal and exotics)

Radiology (small animal, exotics, equine)

MRI (small animal, equine)

My primary research interest is the imaging of ischaemic stroke.

Since 2012, I have been working on subgroup analyses of imaging from the Third International Stroke Trial (IST-3), a large randomised-controlled trial of intravenous alteplase versus control.

In particular, I am investigating whether imaging evidence of arterial obstruction (e.g. hyperdense artery sign as a surrogate marker or flow deficits on CT/MR angiography) and the results from advanced CT/MR perfusion techniques should influence our decision to treat patients with intravenous thrombolytic drugs.  This is especially important in an era where ischaemic stroke treatment is changing with new evidence supporting the use of direct clot retrieval.

I am also developing interests in the use of computational systems for the automated analysis of CT imaging in stroke and natural language processing algorithms for identifying and classifying stroke patients from within very large radiology report datasets.