Upcoming Events

A Celebration of the IDentIFY project and Ten Years of ABIC Oct 22, 2019 09:30 AM - 03:30 PM — Suttie Centre for Teaching & Learning in Healthcare, Medical School Campus, University of Aberdeen
4D flow MRI workshop Oct 22, 2019 12:30 PM - 04:30 PM — ICE Building, Queen Elizabeth University Hospital Glasgow
NRS Mental Health Network Annual Scientific Meeting 2019 Oct 29, 2019 09:00 AM - 04:30 PM — Technology Innovation Centre, 99 George Street, Glasgow
PET is Wonderful Annual Meeting 2019 Oct 29, 2019 09:00 AM - 05:00 PM — Royal Society of Edinburgh, 22-26 George Street, Edinburgh
Scottish Radiological Society Annual General Meeting 2019 Nov 01, 2019 12:00 AM — Principal Grand Central Hotel, Glasgow

People


Your search for Keyword: 'Cardiovascular Imaging' returned 13 Result(s)



Dr Nicolas Aristokleous

My academic and research interests lie on biomedical and biomechanical studies and applications. More specifically, I am working in Image-Based Modelling and in Haemodynamics area with the use of computational fluid dynamics (CFD).

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Professor Edwin van Beek

I am a clinical cardiothoracic radiologist with experience in lung, cardiovascular and oncologic imaging. I am interested in multidisciplinary research approaches with the application of novel imaging techniques and advanced quantitative software tools to provide better analysis of disease states and wish to develop imaging as a biomarker. In addition to the relatively traditional single organ system approach, I am interested in the interactions of these systems within the larger groups of diseases, including COPD, asthma, atherosclerosis and cancer. Towards this end, I intend to develop programs that will appeal to multiple specialities that may not currently be working together within a single group of researchers. Apart from these ideas and interests, I am trained in Clinical Epidemiology and am interested in developing Evidence Based Radiology into clinical practice and build this within the registrar training scheme. It is my firm belief that this will aid in developing an academic career pathway within Radiology. My current role is that of director of the clinical research imaging centre, which houses 3T MRI, 128 PET-CT and 320 detector row CT. This is supported by a GE cyclotron with a fully functional MHRA inspected GMP radiochemistry facility as well as a research laboratory, allowing clinical/research production as well as development of novel radiotracers. An integrated advanced image analysis laboratory completes the centre.

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Mr Alessandro Colombano

The cardiac contractile work is fundamental to maintain heart’s tissue perfusion. Adenosine Triphosphate (ATP) is the main chemical fuel used for this purpose. Almost 90% of ATP in the healthy heart is synthesised through the FAO, while the remaining 10% is produced via the glycolysis pathway. In the Heart Failure (HF) syndrome a switch between these two pathways has been reported: in the early stages of HF the FAO/glycolysis relative rates are unchanged, while in the advanced ones there is a downregulation of the FAO pathway strongly linked to disease’s progression and severity. Thus, assessing the FAO rate would improve patients monitoring and therapy effectiveness. FAO imaging using Positron Emission Tomography (PET) allows its absolute quantification through a tracer labelled with radioactive nuclides, for instance 11C or 18F. Metabolically trapped probes are particularly interesting because they undergo the FAO generating a radioactive metabolite, which is trapped in the mitochondria reflecting the oxidation rate. A novel PET candidate has been designed to be taken up by the myocardium as a conventional fatty acid and would be a FAO substrate; the β-oxidation cycle is then expected to generate a reactive difluoroketone which would be trapped inside the mitochondria and its emitted radioactivity would reflect the FAO rate.

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Dr Craig Daly

I have been using 3D laser scanning microscopy since 1993 to study vascular structure & function.  In recent years my imaging studies have focused on the autonomic innervation of perivascular adipose tissue (PVAT).  During all of these years I have been continually frustrated by the limited 3D visualisation options offered by most microscope-based 3D analysis packages (usually just 'tilt and turn').  A collaboration with the Glasgow School of Art, Digital Design Studio, alerted me to the possibility of importing 3D microscope-based data into sophisticated animation software (i.e. Autodesk Maya & 3Ds Max).  This has led to a new interest in animation & multimedia for teaching, learning & outreach.

If you have a 3D image volume that needs repaired, enhanced or brought to life, please get in touch.

http://www.gla.ac.uk/schools/lifesciences/staff/craigdaly/3dservice/

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Sean Denham


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Dr John Foster


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Dr Maurits Jansen


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Dr Pasquale Maffia

My major interest is the immune response in cardiovascular diseases. Current research activities address the study and imaging of cellular and molecular mechanisms involved in the pathophysiology of atherosclerosis, neointimal formation and hypertension.

Immune responses play a key role in cardiovascular diseases. We have developed techniques to track antigen presenting cells and antigen presentation in the development of vascular immune response (ATVB 2012; Circulation 2014). We have been amongst the first to apply multiphoton microscopy in experimental atherosclerosis (Circulation 2007) and stroke (Stroke 2011) with the aim to define the kinetics and anatomical location of the T cell-antigen presenting cell interactions which underlie vascular immune response in real-time in vivo (Immunity 2015). We are currently developing surface-enhanced Raman spectroscopy for multiplexing molecular imaging of vascular inflammation (Heart 2018). The overall hypothesis is that atherosclerosis is a vascular and not a systemic immune disease. As such, the ultimate goal is to develop new modalities for imaging vascular inflammation and deliver immuno-modulatory treatments directly to the vessel wall.

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Dr Kenneth Mangion


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Dr Giles Roditi


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