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Your search for Keyword: 'Kinetic Modelling' returned 4 Result(s)
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Professor Vin Cunningham
PET Tracer Kinetic Modelling
Mrs Agne Knyzeliene
Neuroinflammation is a common factor in a variety of neurological disorders, including dementia. Thanks to molecular imaging techniques, such as positron emission tomography (PET), the extent of neuroinflammation can be detected in vivo, assisting with diagnosis and monitoring of the disease, as well as benefiting the preclinical research. During my PhD project, I will be studying 18kDa translocator protein (TSPO) as a biomarker for neuroinflammation and validating the use of novel TSPO radiotracers to image dementia-associated neuroinflammation in preclinical dementia models. In addition, I will assess the cellular distribution of TSPO in the brain under physiological and pathophysiological conditions.