Medical Imaging Convention [rescheduled] Mar 09, 2021 - Mar 10, 2021 — National Exhibition Centre, Birmingham, England
9th SINAPSE Neuro-oncology Imaging Meeting [rescheduled] Mar 11, 2021 09:30 AM - 03:30 PM — West Park Conferencing & Events, 319 Perth Road, Dundee DD2 1NN
Total Body PET 2020 conference [rescheduled] Jun 05, 2021 - Jun 07, 2021 — McEwan Hall, University of Edinburgh

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

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ADHD Addictions Ageing Alzheimer's Anaesthesia Artificial Intelligence Attention Autism Bioorganic chemistry Bipolar disorder Brain temperature CT Cardiac imaging Cardiovascular Imaging Carotid Doppler ultrasound Cerebral atrophy Chemistry Clinical decision support Cognitive Control Computer vision DTI-tractography Data protection Database Deep Learning Dementia Depression Diffusion imaging Disorders of Consciousness Doppler ultrasound EEG ERP Episodic memory Evidence Based Radiology Executive Function Fetal and Child development Field-cycling Free radicals Functional Connectivity Functional MRI (fMRI) Image analysis Image processing Image segmentation Imaging biomarkers Imitation Impaired Consciousness Kinetic Modelling Lacunar stroke Language Large animal imaging Leukoaraiosis Lung Imaging MRA MRI hardware MRI pulse sequences MRS Machine Learning Magnetization transfer Medical visualization Memory Meta-analysis Microvascular MRI Molecular Imaging Multicentre studies Muscle Imaging and Measurement NMR relaxometry Neurodevelopment Neuroinformatics Neurology Neuroradiology Novel Radiotracers Novel imaging methods Nuclear Medicine Oncologic Imaging Oncology Optical imaging PET Parallel computing Perfusion imaging (CT and MR) Permeability imaging (MR) Physics Preclinical Imaging Predictive Classification Psychiatry Radiochemistry Radiology Radiomics Retinal imaging SPECT Schizophrenia Semantic Memory Simulation Small vessel disease Statistics Stroke Structural imaging TBI Texture analysis Thrombolysis Time series analyses Translational Imaging Ultra-high field MRI Ultrasound White matter disease

Dr Deepayan Bhowmik


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Professor Luc Bidaut


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Mr Thomas Biggans


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Professor David Birch


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Dr Viveka Biswas

Stroke medicine, Neurology, Neuroradiology

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Dr Douglas Black


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Adele Blair

Description of PhD:

 

The translocator protein 18 kDa (TSPO, formerly known as the peripheral benzodiazepine receptor) is found at high levels in the kidney, lung, heart and at low concentration in the brain. TSPO is associated with initial inflammatory processes in the early stages of neurological diseases such as Parkinson’s and Alzheimer’s diseases and after brain injury caused by stroke or head trauma. TSPO has therefore significant potential as a marker of regions affected by these conditions. While radioligands have been developed for TSPO these suffer from high nonspecific binding and relatively low brain uptake. The aim of this project is to develop a new generation of molecular tracers which can act as effective imaging agents for TSPO. A new synthetic approach for the preparation of a small library of compounds based on the phenoxyphenylacetamide core structure will be developed and tested for affinity with TSPO. This will allow the development of a structure activity relationship model ultimately generating a lead compound which can radiolabelled for in vivo imaging of TSPO. An additional feature of this research programme will be the design of target compounds with multi-labelling positions allowing these compounds to be used for either PET and SPECT imaging (In collaboration with Dr Sally Pimlott, University of Glasgow). The structures of these compounds also have the potential to fluoresce and thus may find application in optical imaging. A significant portion of this PhD studentship will be carried out in the department of chemistry (GU), thus further strengthening the collaboration between the ScotCHEM and SINAPSE pooling initiatives. The research will be carried out in collaboration with Molecular NeuroImaging, MNI, a company based in Connecticut who develop radioligands as tools for drug development for neurodegenerative and neuropsychiatric disorders (Dr Gilles Tamagnan). MNI will consult on the key objectives of the research programme as well as provide a placement for the PhD student to experience the use of clinical trials and PET/SPECT radiochemistry in an industrial setting.

 

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Dr Gordon Blair

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Dr William Boadu

Stroke;  Hereditary cerebral small vessel arteriopathy; General Neurology

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Dr James Boardman


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