Medical Imaging Convention [rescheduled] Mar 09, 2021 - Mar 10, 2021 — National Exhibition Centre, Birmingham, England
9th SINAPSE Neuro-oncology Imaging Meeting [rescheduled] Mar 11, 2021 09:30 AM - 03:30 PM — West Park Conferencing & Events, 319 Perth Road, Dundee DD2 1NN
Total Body PET 2020 conference [rescheduled] Jun 05, 2021 - Jun 07, 2021 — McEwan Hall, University of Edinburgh

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Blood oxygen level dependent (BOLD) MRI: A novel technique for the detection of myocardial ischemia

Author(s): M. Egred, G. D. Waiter, A. Al-Mohammad, S. I. K. Semple, T. W. Redpath, S. Walton

Abstract:
Background: Blood oxygen level dependent (BOLD) T2* MRI detects signal variance within the myocardium based on changes in the deoxyhaemoglobin level following pharmacological stress, and it has the potential to identify areas of myocardial ischemia. The aim of the present study was to assess the utility of BOLD T2* MRI in the detection of myocardial ischemia in patients with an existing diagnosis of coronary artery disease. Method: Twenty-one patients with established three-vessel coronary artery disease on coronary angiography underwent rest and dipyridamole stress MRI using a double breath-hold T2* weighted ECG gated sequence. Analysis was performed on multiple short-axis slices of the heart, projected as a bull's eye. The myocardium was divided into three coronary territories, yielding 63 territories in total. A signal change between rest and stress of more than +/- 4% was significant, implying a change in deoxyhaemoglobin concentration. A signal decrease or no changes denote the presence of ischemia, while a signal increase indicates no ischemia. Results: All images were of sufficient quality for signal intensity analysis. In 12/63 territories (19%), a significant signal increase following stress was detected. A significant signal decrease was detected in 34/63 territories (54%), and in 17/63 territories (27%) there was a nonsignificant change. The presence of a perfusion defect was identified, therefore, in 51/63 (81%), based on the signal difference between rest and stress. Conclusion: Changes in myocardial oxygen level appear to be detectable by BOLD T2* MRI without using contrast media. Further, larger comparative studies are required to evaluate the diagnostic and prognostic impact of this technique and to compare it to the gold standard methods for the detection of myocardial ischemia. (C) 2006 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

Full version: Available here

Click the link to go to an external website with the full version of the paper


ISBN: 0953-6205
Publication Year: 2006
Periodical: European Journal of Internal Medicine
Periodical Number: 8
Volume: 17
Pages: 551-555
Author Address: