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Diffuse brain oedema in idiopathic intracranial hypertension: a quantitative magnetic resonance imaging study

Author(s): M. E. Bastin, S. Sinha, A. J. Farrall, J. M. Wardlaw, I. R. Whittle

Abstract:
Objectives: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging. Methods: Values for the mean diffusivity of water (<D>) and the proton longitudinal relaxation time (T1) were measured for various brain regions in 10 patients with idiopathic intracranial hypertension and 10 age, sex, and weight matched controls. Results: No significant differences in <D> and T1 values were found between patient and control groups in any of the brain regions investigated. Conclusions: The results suggest that idiopathic intracranial hypertension is not associated with abnormalities of convective transependymal water flow leading to diffuse brain oedema.

Full version: Available here

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ISBN: 0022-3050
Publication Year: 2003
Periodical: Journal of Neurology Neurosurgery and Psychiatry
Periodical Number: 12
Volume: 74
Pages: 1693-1696
Author Address: