Data Sciences and Brain Health across the Life Course session in 2020 SICSA Conference Oct 01, 2020 01:15 PM - 03:15 PM — Virtual Meeting (online)
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eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Fluorine in health care Organofluorine containing blockbuster drugs

Author(s): D. O'Hagan

Abstract:
Organic fluorine compounds have had a profound impact on the development of bioactives for the modern pharmaceuticals market It is estimated that up to 20% of pharmaceuticals prescribed or administered in the clinic contain a fluorine atom and 30% of the leading 30 blockbuster drugs by sales contain a fluorine In this Highlight review the top 10 fluorine containing pharmaceuticals (by US Sales in 2008) are highlighted By this measure these are currently the most significant fluorinated compounds impacting on health care They embrace statins (Lipitor Crestor Vytorin Zetia/Ezetimibe) anti-inflammatories (fluticasone propionate Celebrex) antacid (Prevacid) antidepressants (Lexapro) neuroleptics (Risperdal) and antibiotics (Levaquin) In each case the structures and modes of action of these important drugs compounds are reviewed and representative synthetic routes are highlighted (C) 2010 Published by Elsevier BV

Full version: Available here

Click the link to go to an external website with the full version of the paper


ISBN: 0022-1139
Publication Year: 2010
Periodical: Journal of Fluorine Chemistry
Periodical Number: 11
Volume: 131
Pages: 1071-1081
Author Address: