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SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists. **Unfortunately these do not currently work in browsers**

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Online Short Courses

Fluorometabolite biosynthesis and the fluorinase from Streptomyces cattleya

Author(s): H. Deng, D. O'Hagan, C. Schaffrath

This review outlines the recent developments in uncovering the enzymes and intermediates involved in fluorometabolite biosynthesis in the bacterium Streptomyces cattleya. A particular emphasis is placed on the purification and characterisation of the fluorinase, the C-F bond forming enzyme which initiates the biosynthesis. Nature has hardly developed a biochemistry around fluorine, yet fluorinated organics are important commercial entities, therefore a biotransformation from inorganic to organic fluorine is novel and of contemporary interest.

Full version: Available here

Click the link to go to an external website with the full version of the paper

ISBN: 0265-0568
Publication Year: 2004
Periodical: Natural Product Reports
Periodical Number: 6
Volume: 21
Pages: 773-784
Author Address: