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Fluorosugars: synthesis of the 2,3,4-trideoxy-2,3,4-trifluoro hexose analogues of D-glucose and D-altrose and assessment of their erythrocyte transmembrane transport

Author(s): Stefano Bresciani, Tomas Lebl, Alexandra M. Z. Slawin, David O'Hagan

The 2,3,4-trideoxy-2,3,4-trifluoro hexose analogues of d-glucose and d-altrose were prepared and characterised and these novel sugar analogues were explored by 2D-(19)F-EXSY NMR for their potential to cross erythrocyte (red blood cell) membranes, by comparison with the well known capacity of erythrocytes to transport d-glucose.

Full version: Available here

Click the link to go to an external website with the full version of the paper

ISBN: 1364-548X
Publication Year: 2010
Periodical: Chem Commun (Camb)
Periodical Number: 30
Volume: 46
Pages: 5434-6
Author Address: