2022 PET Pharmacokinetic Modelling Course May 26, 2022 - May 28, 2022 — Edinburgh
Brain and Brain PET 2022 May 29, 2022 - Jun 01, 2022 — Glasgow
2022 SINAPSE ASM Jun 13, 2022 - Jun 14, 2022 — Strathclyde University, Glasgow
2022 OHBM Annual Meeting Jun 19, 2022 - Jun 23, 2022 — Glasgow, SEC


SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists. **Unfortunately these do not currently work in browsers**

Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

How does the degree of carotid stenosis affect the accuracy and interobserver variability of magnetic resonance angiography?

Author(s): J. M. Wardlaw, S. C. Lewis, P. Humphrey, G. Young, D. Collie, C. P. Warlow

Objectives-The accuracy of magnetic resonance angiography (MRA) was determined in patients with recently symptomatic tight (80%-99%) carotid stenosis (on Doppler ultrasound), and the effect of stenosis severity on the accuracy and interobserver variability of MRA was studied. Methods-Forty four consecutive patients undergoing intra-arterial angiography (IAA) before carotid endarterectomy were prospectively studied, in two centres with identical MR scanners and sequences. All patients had undergone Doppler ultrasound, showing a 70% or worse carotid stenosis on the symptomatic side. MRA and IAA were done during the same admission. The MRA films were each independently and blindly read for percentage stenosis (signal gap if present) by four observers. The IA angiograms were read separately by one observer, blind to symptoms, and Doppler and MRA results. Results-Signal gaps on MRA were seen in stenoses ranging from 67% to 99% on intraarterial angiography. Magnetic resonance angiograms consistently overestimated the percentage stenosis according to intraarterial angiography. Clinically significant misclassification of stenosis occurred according to MRA in 7% of patients, and was more frequent as carotid stenosis increased. Conclusion-Significant diagnostic errors occur with MRA in patients with tight carotid stenosis. Any morbidity occurring as a result of misclassification by MRA is likely to be offset by the avoidance of complications; however, this could only be determined with certainty in a randomised controlled trial.

Full version: Available here

Click the link to go to an external website with the full version of the paper

ISBN: 0022-3050
Publication Year: 2001
Periodical: Journal of Neurology Neurosurgery and Psychiatry
Periodical Number: 2
Volume: 71
Pages: 155-160
Author Address: