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eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

In ovo non-invasive quantification of the myocardial function and mass of chick embryos using magnetic resonance imaging

Author(s): W. M. Holmes, C. McCabe, J. M. Mullin, B. Condon, M. M. Bain

Abstract:
Magnetic resonance imaging (MRI) has evolved as one of the major non-invasive tools to study healthy and diseased hearts in animal models, especially rodent models. Even though, the chick embryo has long been used as a model for cardiovascular research, MRI has not yet been used for in vivo cardiac studies. Part of the reason for this is the difficulty in monitoring the ECG and respiration of the chick embryo in the magnet for gating purposes. To overcome this complication, this paper presents the use of retrospective Cine MRI to measure the cardiac function of chick embryos in ovo for the first time, without the need for respiratory or cardiac gating. The resulting left ventricular functional parameters, from six chick embryos at 20 days of incubation, were (mean +/-SD) EDV 69 +/- 15 mu L, ESV 31 +/- 7 mu L, SV 38 +/- 9 mu L and EF 54.5 +/- 2%. The use of retrospective Cine MRI at earlier stages of development is also discussed and difficulties have been highlighted. Copyright (C) 2009 John Wiley & Sons, Ltd.

Full version: Available here

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ISBN: 0952-3480
Publication Year: 2009
Periodical: Nmr in Biomedicine
Periodical Number: 7
Volume: 22
Pages: 745-752
Author Address: Holmes, WM Univ Glasgow, Wellcome Surg Inst, GEMRIC, Fac Med, Garscube Estate,Bearsden Rd, Glasgow G61 1QH, Lanark, Scotland Univ Glasgow, Wellcome Surg Inst, GEMRIC, Fac Med, Glasgow G61 1QH, Lanark, Scotland So Gen Hosp, Inst Neurol Sci, Glasgow G51 4TF, Lanark, Scotland Univ Glasgow, Sch Vet, Div Cell Sci, ICM, Glasgow G61 1QH, Lanark, Scotland