Medical Imaging Convention [rescheduled] Sep 15, 2021 - Sep 16, 2021 — National Exhibition Centre, Birmingham, England
2021 SINAPSE ASM Sep 16, 2021 - Sep 17, 2021 — Technology & Innovation Centre, University of Strathclyde, 99 George Street, Glasgow
Total Body PET 2021 conference [rescheduled] Sep 22, 2021 - Sep 24, 2021 — Virtual Meeting (online)
PET is Wonderful Annual Meeting 2021 Oct 26, 2021 12:00 AM — Virtual Meeting (online)


SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.

Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Isolation and characterisation of 5 '-fluorodeoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya

Author(s): C. Schaffrath, H. Deng, D. O'Hagan

5'-Fluorodeoxyadenosine synthase, a C-F bond-forming enzyme, has been purified from Streptomyces cattleya. The enzyme mediates a reaction between inorganic fluoride and S-adenosyl-L-methionine (SAM) to generate 5'-fluoro-5'-deoxy-adenosine. The molecular weight of the monomeric protein is shown to be 32.2 kDa by electrospray mass spectrometry. The kinetic parameters for SAM (K-m 0.42 mM, V-max 1.28 U/mg) and fluoride ion (K-m 8.56 mM, V-max 1.59 U/mg) have been evaluated. Both S-adenosyl-L-homocysteine (SAH) and sinefungin were explored as inhibitors of the enzyme. SAH emerged as a potent competitive inhibitor (K-i 29 muM) whereas sinefungin was only weakly inhibitory. (C) 2003 Published by Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies.

Full version: Available here

Click the link to go to an external website with the full version of the paper

ISBN: 0014-5793
Publication Year: 2003
Periodical: Febs Letters
Periodical Number: 1-3
Volume: 547
Pages: 111-114
Author Address: