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SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.

Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Manganese requirement and toxicity in patients on home parenteral nutrition

Author(s): N. Reynolds, A. Blumsohn, J. P. Baxter, G. Houston, C. R. Pennington

Two patients who were receiving home parenteral nutrition complained of vague neurological symptoms of such severity that they underwent full clinical appraisal. The only positive finding was that plasma manganese concentrations were greater than twice the upper 95% confidence interval of normal (7-27 nmol/l). In the light of this result all nine patients receiving home parenteral nutrition underwent evaluation for possible manganese toxicity. One other patient had serum manganese concentrations exceeding twice the upper limit (127 nmol/l). The three patients with elevated serum Mn had evidence of manganese deposition in the brain on magnetic resonance imaging scanning. In contrast two patients with normal plasma results had negative scans. Patient susceptibility appears very variable. We suggest that current amounts of trace elements provided in nutrition solutions may be a potential source of nutrient activity. The fine tuning of supply and demand may be difficult on account of a limited range of commercially available trace element solutions.

Full version: Available here

Click the link to go to an external website with the full version of the paper

ISBN: 0261-5614
Publication Year: 1998
Periodical: Clinical Nutrition
Periodical Number: 5
Volume: 17
Pages: 227-230
Author Address: Pennington, CR Univ Dundee, Ninewells Hosp & Med Sch, Dept Digest Dis & Clin Nutr, Dundee DD1 9SY, Scotland Univ Dundee, Ninewells Hosp & Med Sch, Dept Digest Dis & Clin Nutr, Dundee DD1 9SY, Scotland