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eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Measurement of regional brain temperature using proton spectroscopic imaging: validation and application to acute ischemic stroke

Author(s): I. Marshall, B. Karaszewski, J. M. Wardlaw, V. Cvoro, K. Wartolowska, P. A. Armitage, T. Carpenter, M. E. Bastin, A. Farrall, K. Haga

Abstract:
A magnetic resonance proton spectroscopic imaging (SI) technique was developed to measure regional brain temperatures in human subjects. The technique was validated in a homogeneous phantom and in four healthy volunteers. Simulations and calculations determined the theoretical measurement precision as approximately +/-0.3 degrees C for individual 1-ml voxels. In healthy volunteers, repeated measurements oil individual voxels had all S.D.= 1.2 degrees C. In a clinical study. 40 patients with acute ischemic stroke were imaged within 26 h (mean. 10 h) of onset. Temperatures were highest in the region that appeared abnormal (i.e.. ischemic) on diffusion-weighted imaging (DWI) compared with a normal-appearing brain. The mean temperature difference between the DWI "lesion" area and the "normal brain" was 0.17 degrees C [P < 10(-3), range, 2.45 degrees C (hotter)-2.17 degrees C (cooler)]. Noninvasive temperature measurement by SI has sufficient precision to be used in Studies of pathophysiology in stroke and in other brain disorders and to monitor therapies. (C) 2006 Elsevier Inc. All rights reserved.

Full version: Available here

Click the link to go to an external website with the full version of the paper


ISBN: 0730-725X
Publication Year: 2006
Periodical: Magnetic Resonance Imaging
Periodical Number: 6
Volume: 24
Pages: 699-706
Author Address: