SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists. **Unfortunately these do not currently work in browsers**

Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Neuroimaging in acute ischaemic stroke: insights into unanswered questions of pathophysiology

Author(s): J. M. Wardlaw

The treatment of acute ischaemic stroke is based on the principle that there is ischaemic but still potentially salvageable tissue that could be rescued if blood flow could be restored quickly. It is assumed that salvage might only be possible in the first few hours, and that infarct expansion is a direct result of failed recanalization of the main artery. This concept arose from experimental work in the 1970s, supported more recently by studies using imaging to identify penumbral tissue. However, although magnetic resonance diffusion and perfusion imaging is a way of imaging penumbral tissue and has been around for over a decade, it is not an easy technique to apply in practice and its use has produced conflicting results. Computed tomography perfusion, and any other tissue perfusion imaging technique, is likely to encounter the same difficulties. Indeed many factors, other than the presence of a diffusion-perfusion mismatch acutely, may determine or influence ultimate tissue fate even days after the stroke, and in turn, clinical outcome. Many of these potential influences are beginning to emerge from studies using different forms of imaging at later times after stroke. This review will explore the information now emerging from imaging studies in large artery ischaemic stroke to summarize knowledge to date and indicate unresolved issues for the future.

Full version: Available here

Click the link to go to an external website with the full version of the paper

ISBN: 0954-6820
Publication Year: 2010
Periodical: Journal of Internal Medicine
Periodical Number: 2
Volume: 267
Pages: 172-190
Author Address: Wardlaw, JM Univ Edinburgh, Western Gen Hosp, SINAPSE Collaborat, SFC Brain Imaging Res Ctr,Div Clin Neurosci, Crewe Rd, Edinburgh EH4 2EX, Midlothian, Scotland Univ Edinburgh, Western Gen Hosp, SINAPSE Collaborat, SFC Brain Imaging Res Ctr,Div Clin Neurosci, Edinburgh EH4 2EX, Midlothian, Scotland