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eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Non spiral and spiral (helical) flow patterns in stenoses - In vitro observations using spin and gradient echo magnetic resonance imaging (MRI) and computational fluid dynamic modeling

Author(s): P. A. Stonebridge, C. Buckley, A. Thompson, J. Dick, G. Hunter, J. A. Chudek, J. G. Houston, J. J. F. Belch

Abstract:
Aim. Physiological blood flow patterns are themselves poorly understood despite their impact on arterial disease. Stable spiral (helical) laminar flow (SLF) has been observed in normal subjects. The purpose of the present study is to develop a method of magnetic resonance (MR) flow pattern visualization and to analyze spiral and non-spiral flow patterns with and without luminal narrowing in vitro. The flow conditions were then modeled using computational fluid dynamics (Star-CD). Methods. Laminar integrity was examined in a flow-rig using spin and gradient echo magnetic resonance imaging (MRI) in non-stenosed and stenosed conduits in the presence of non-spiral and spiral flow. Results. No difference was observed in a non-stenosed conduit between non-spiral and spiral flow. In the presence of a stenosis spiral flow preserves flow velocity coherence whereas non-spiral flow increasingly lost coherence beginning proximal to the stenosis. Computational fluid dynamic modeling of the in vitro experiment showed marked differences between the 2 flow patterns. Non-spiral flow produced greater inwardly directed forces just beyond the stenosis and greater outward pressures at more distal sites. The near wall turbulent energy was up to 700% less with spiral flow over non-spiral flow beyond the stenosis. Conclusion. Spiral flow appears to offer clear flow profile stabilizing advantages over non-spiral flow, by significantly reducing the turbulence caused by a stenosis. Spiral flow also produces lower forces acting on the vessel wall.

Full version: Available here

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ISBN: 0392-9590
Publication Year: 2004
Periodical: International Angiology
Periodical Number: 3
Volume: 23
Pages: 276-283
Author Address: Stonebridge, PA Ninewells Hosp & Med Sch, Inst Cardiovasc Ree, Dept Surg, Dundee, Scotland Ninewells Hosp & Med Sch, Inst Cardiovasc Ree, Dept Surg, Dundee, Scotland Univ Cambridge, Dept Chem Engn, Magnet Resonance Res Ctr, Cambridge, England Ninewells Hosp & Med Sch, Dundee, Scotland Ninewells Hosp & Med Sch, Inst Cardiovasc Res, Dept Vasc Med, Dundee, Scotland Univ Dundee, Dept Chem, Dundee, Scotland