4th International Conference on Medical Imaging with Deep Learning Jul 07, 2021 - Jul 09, 2021 — Virtual Meeting (online)
Medical Image Understanding and Analysis Conference 2021 Jul 12, 2021 - Jul 14, 2021 — Virtual Meeting (online)
Medical Imaging Convention [rescheduled] Sep 15, 2021 - Sep 16, 2021 — National Exhibition Centre, Birmingham, England
2021 SINAPSE ASM Sep 16, 2021 - Sep 17, 2021 — Technology & Innovation Centre, University of Strathclyde, 99 George Street, Glasgow
Total Body PET 2021 conference [rescheduled] Sep 22, 2021 - Sep 24, 2021 — Virtual Meeting (online)

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Persistent infarct hyperintensity on diffusion-weighted imaging late after stroke indicates heterogeneous, delayed, infarct evolution

Author(s): C. S. Rivers, J. M. Wardlaw, P. A. Armitage, M. E. Bastin, T. K. Carpenter, V. Cvoro, P. J. Hand, M. S. Dennis

Abstract:
Background and Purpose - Some infarcts have persistently hyperintense areas on diffusion-weighted MRI ( DWI) even at 1 month after stroke, whereas others have become isointense to normal brain. We hypothesized that late DWI hyperintensity reflected different infarct evolution compared with areas that were isointense by 1 month. Methods - We recruited patients prospectively with ischemic stroke, performed DWI and perfusion-weighted MRI ( PWI) on admission, at 5 days, 14 days, and 1 month after stroke, and assessed functional outcome at 3 months ( Rankin Scale). Patient characteristics and DWI/PWI values were compared for patients with or without "still hyperintense" infarct areas on 1-month DWI. Results - Among 42 patients, 27 ( 64%) had "still hyperintense" infarct regions at 1 month, mostly in white matter. Patients with "still hyperintense" regions at 1 month had lower baseline apparent diffusion coefficient ratio ( ADCr; mean +/- SD 0.76 +/- 0.12 versus 0.85 +/- 0.12; hyperintense versus isointense; P < 0.05), prolonged reduction of ADCr ( repeated-measures ANOVA; P < 0.01), no difference in baseline perfusion but delayed normalization of mean transit time ( P < 0.05) and cerebral blood flow ratios ( repeated measures ANOVA; P < 0.05), initially more severe stroke, and worse 3-month outcome than patients whose lesions were isointense by 1 month. Conclusion - The late DWI lesion hyperintensity emphasizes the heterogeneity in temporal evolution of stroke injury and suggests ongoing " ischemia." Lower baseline ADCr precedes delayed perfusion normalization, suggesting that worse cell swelling impedes reperfusion. Further study is required to determine underlying mechanisms and any potential for subacute intervention to improve recovery.

Full version: Available here

Click the link to go to an external website with the full version of the paper


ISBN: 0039-2499
Publication Year: 2006
Periodical: Stroke
Periodical Number: 6
Volume: 37
Pages: 1418-1423
Author Address: