NRS Mental Health Network Annual Scientific Meeting 2020 Nov 04, 2020 09:00 AM - 05:30 PM — Virtual Meeting (online)
Scottish Radiological Society Annual General Meeting 2020 Nov 06, 2020 09:30 AM - 03:30 PM — Virtual Meeting (online)
Megastars in Molecular Imaging seminars Nov 09, 2020 - Nov 10, 2020 — Virtual Meeting (online)
IPEM educational meeting: Artificial Intelligence in MRI Nov 18, 2020 12:00 AM — Virtual Meeting (online)
Blood-Brain Barrier Symposium Nov 23, 2020 09:30 AM - 05:00 PM — Virtual Meeting (online)

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

Author(s): C. J. Willer, E. K. Speliotes, R. J. F. Loos, S. X. Li, C. M. Lindgren, I. M. Heid, S. I. Berndt, A. L. Elliott, A. U. Jackson, C. Lamina, G. Lettre, N. Lim, H. N. Lyon, S. A. McCarroll, K. Papadakis, L. Qi, J. C. Randall, R. M. Roccasecca, S. Sanna, P. Scheet, M. N. Weedon, E. Wheeler, J. H. Zhao, L. C. Jacobs, I. Prokopenko, N. Soranzo, T. Tanaka, N. J. Timpson, P. Almgren, A. Bennett, R. N. Bergman, S. A. Bingham, L. L. Bonnycastle, M. Brown, N. L. P. Burtt, P. Chines, L. Coin, F. S. Collins, J. M. Connell, C. Cooper, G. D. Smith, E. M. Dennison, P. Deodhar, P. Elliott, M. R. Erdos, K. Estrada, D. M. Evans, L. Gianniny, C. Gieger, C. J. Gillson, C. Guiducci, R. Hackett, D. Hadley, A. S. Hall, A. S. Havulinna, J. Hebebrand, A. Hofman, B. Isomaa, K. B. Jacobs, T. Johnson, P. Jousilahti, Z. Jovanovic, K. T. Khaw, P. Kraft, M. Kuokkanen, J. Kuusisto, J. Laitinen, E. G. Lakatta, J. Luan, R. N. Luben, M. Mangino, W. L. McArdle, T. Meitinger, A. Mulas, P. B. Munroe, N. Narisu, A. R. Ness, K. Northstone, S. O'Rahilly, C. Purmann, M. G. Rees, M. Ridderstraale, S. M. Ring, F. Rivadeneira, A. Ruokonen, M. S. Sandhu, J. Saramies, L. J. Scott, A. Scuteri, K. Silander, M. A. Sims, K. Song, J. Stephens, S. Stevens, H. M. Stringham, Y. C. L. Tung, T. T. Valle, C. M. Van Duijn, K. S. Vimaleswaran, P. Vollenweider, G. Waeber, C. Wallace, R. M. Watanabe, D. M. Waterworth, N. Watkins, J. C. M. Witteman, E. Zeggini, G. J. Zhai, M. C. Zillikens, D. Altshuler, M. J. Caulfield, S. J. Chanock, I. S. Farooqi, L. Ferrucci, J. M. Guralnik, A. T. Hattersley, F. B. Hu, M. R. Jarvelin, M. Laakso, V. Mooser, K. K. Ong, W. H. Ouwehand, V. Salomaa, N. J. Samani, T. D. Spector, T. Tuomi, J. Tuomilehto, M. Uda, A. G. Uitterlinden, N. J. Wareham, P. Deloukas, T. M. Frayling, L. C. Groop, R. B. Hayes, D. J. Hunter, K. L. Mohlke, L. Peltonen, D. Schlessinger, D. P. Strachan, H. E. Wichmann, M. I. McCarthy, M. Boehnke, I. Barroso, G. R. Abecasis, J. N. Hirschhorn, Control Wellcome Trust Case, Consortium Giant

Abstract:
Common variants at only two loci, FTO and MC4R, have been reproducibly associated with body mass index (BMI) in humans. To identify additional loci, we conducted meta-analysis of 15 genome-wide association studies for BMI (n > 32,000) and followed up top signals in 14 additional cohorts (n > 59,000). We strongly confirm FTO and MC4R and identify six additional loci (P < 5 x 10(-8)): TMEM18, KCTD15, GNPDA2, SH2B1, MTCH2 and NEGR1 (where a 45-kb deletion polymorphism is a candidate causal variant). Several of the likely causal genes are highly expressed or known to act in the central nervous system (CNS), emphasizing, as in rare monogenic forms of obesity, the role of the CNS in predisposition to obesity.

Full version: Available here

Click the link to go to an external website with the full version of the paper


ISBN: 1061-4036
Publication Year: 2009
Periodical: Nature Genetics
Periodical Number: 1
Volume: 41
Pages: 25-34
Author Address: