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eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Substrate specificity in enzymatic fluorination. The fluorinase from Streptomyces cattleya accepts 2 '-deoxyadenosine substrates

Author(s): S. L. Cobb, H. Deng, A. R. McEwan, J. H. Naismith, D. O'Hagan, D. A. Robinson

Abstract:
The fluorinase enzyme from Streptomyces cattleya displays an unusual ability in biocatalysis in that it forms a C - F bond. We now report that the enzyme will accept 2'-deoxyadenosine in place of adenosine substrates, and structural evidence reveals a reorganisation in hydrogen bonding to accommodate this substrate series. It emerges from this study that the enzyme does not require a planar ribose conformation of the substrate to catalyse C - F bond formation.

Full version: Available here

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ISBN: 1477-0520
Publication Year: 2006
Periodical: Organic & Biomolecular Chemistry
Periodical Number: 8
Volume: 4
Pages: 1458-1460
Author Address: