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eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Synthesis of (E)-2,3 ',4,5 '-tetramethoxy[2-C-11]stilbene

Author(s): L. Schweiger, S. Craib, A. Welch, T. A. D. Smith

Abstract:
In this paper, we describe the radiosynthesis of the compound (E)-2,3',4,5'-tetramethoxy[2-C-11]stilbene, a potential, universal tumour positron emission tomography imaging agent. The production of (E)-2,3',4,5'-tetramethoxy[2-C-11]stilbene was carried out via C-11-methylation of (E)-2-(hydroxy)-3',4,5'-trimethoxystilbene by using [C-11]methyl trifluoromethanesulfonate ([C-11]methyl triflate). (E)-2,3',4,5'-tetramethoxy[2-C-11]stilbene was obtained with a radiochemical purity greater than 95% in a 20 +/- 2% decay-corrected radiochemical yield, based upon [C-11]carbon dioxide. Synthesis, purification and formulation were completed on an average of 30 min following the end of bombardment (EOB). The specific radioactivity obtained was 1. 9 +/- 0.6 GBq/mu mol at EOB. Copyright (C) 2007 John Wiley & Sons, Ltd.

Full version: Available here

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ISBN: 0362-4803
Publication Year: 2007
Periodical: Journal of Labelled Compounds & Radiopharmaceuticals
Periodical Number: 13-14
Volume: 50
Pages: 1206-1210
Author Address: