Scottish Clinical Imaging Network (SCIN) Annual Event 2020 [postponed] Apr 30, 2020 09:00 AM - 04:00 PM — Glasgow Caledonian University
NCITA National Conference: Translating Imaging Biomarkers for Improved Patient Outcomes [postponed] May 05, 2020 10:00 AM - 05:00 PM — New Hunt's House, Guy's Campus, King's College London
Scottish Radiological Society Spring Meeting 2020 [postponed] May 15, 2020 09:00 AM - 04:10 PM — Centre for Health Science, Inverness
2020 SINAPSE ASM Jun 19, 2020 09:00 AM - 05:00 PM — Virtual Meeting (online)
3rd International Conference on Medical Imaging with Deep Learning Jul 06, 2020 - Jul 08, 2020 — Palais des congrès, Montréal, Canada

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Computed tomography and magnetic resonance perfusion imaging in ischemic stroke: definitions and thresholds

Author(s): K. A. Dani, R. G. Thomas, F. M. Chappell, K. Shuler, M. J. MacLeod, K. W. Muir, J. M. Wardlaw

Abstract:
OBJECTIVE: Cerebral perfusion imaging with computed tomography (CT) or magnetic resonance (MR) is widely available. The optimum perfusion values to identify tissue at risk of infarction in acute stroke are unclear. We systematically reviewed CT and MR perfusion imaging in acute ischemic stroke. METHODS: We searched for papers on MR or CT perfusion performed <24 hours after stroke that assessed perfusion thresholds, mean perfusion lesion values, or lesion volumes. We extracted definitions and perfusion values. We compared definitions and evaluated perfusion thresholds for "nonviable"/"at risk" and "at risk"/"not at risk tissue" thresholds. RESULTS: Among 7,152 papers, 69 met inclusion criteria for analysis of definitions (49 MR and 20 CT), 21 MR (n = 551), and 10 CT (n = 266) papers, median sample size 22, provided thresholds. We found multiple definitions for tissue states, eg, tissue at risk, 18; nonviable tissue, 12; 16, no definition. Perfusion parameters varied widely; eg, 9 different MR, 6 different CT parameters for the "at risk"/"not at risk threshold." Median threshold values varied up to 4-fold, eg, for the "at risk"/"not at risk threshold," median cerebral blood flow ranged from 18 to 37ml/100g/min; mean transit time from 1.8 to 8.3 seconds relative to the contralateral side. The influence of reperfusion and duration of ischemia could not be assessed. INTERPRETATION: CT and MR perfusion imaging viability thresholds in stroke are derived from small numbers of patients, variable perfusion analysis methods and definitions of tissue states. Greater consistency of methods would help determine reliable perfusion viability values for wider clinical use of perfusion imaging.

Full version: Available here

Click the link to go to an external website with the full version of the paper


ISBN: 1531-8249 (Electronic) 0364-5134 (Linking)
Publication Year: 2011
Periodical: Ann Neurol
Periodical Number: 3
Volume: 70
Pages: 384-401
Author Address: Department of Neurology, Institute of Neurological Sciences, University of Glasgow Southern General Hospital, Glasgow, Scotland.