Scottish Radiological Society Spring Meeting 2022 May 20, 2022 09:00 AM - 05:00 PM — Rowallan Castle, Ayrshire
2022 PET Pharmacokinetic Modelling Course May 26, 2022 - May 28, 2022 — Edinburgh
Brain and Brain PET 2022 May 29, 2022 - Jun 01, 2022 — Glasgow
2022 SINAPSE ASM Jun 13, 2022 - Jun 14, 2022 — Strathclyde University, Glasgow
2022 OHBM Annual Meeting Jun 19, 2022 - Jun 23, 2022 — Glasgow, SEC


SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists. **Unfortunately these do not currently work in browsers**

Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Assessing the performance of atlas-based prefrontal brain parcellation in an aging cohort

Author(s): B. S. Aribisala, S. R. Cox, K. J. Ferguson, S. E. MacPherson, A. M. MacLullich, N. A. Royle, M. C. Valdes Hernandez, M. E. Bastin, I. J. Deary, J. M. Wardlaw

OBJECTIVE: It is unclear whether atlas-based parcellation is suitable in aging cohorts because age-related brain changes confound the performance of automatic methods. We assessed atlas-based parcellation of the prefrontal lobe in an aging population using visual assessment and volumetric and spatial concordance. METHODS: We used an atlas-based approach to parcellate brain MR images of 90 non-demented healthy adults, aged 72.7 +/- 0.7 years, and assessed performance. RESULTS: Volumetric assessment showed that both single-atlas- and multi-atlas-based methods performed acceptably (intraclass correlation coefficient [ICC], 0.74-0.76). Spatial overlap measurements showed that multi-atlas (dice coefficient [DC], 0.84) offered an improvement over the single-atlas (DC, 0.75-0.78) approach. Visual assessment also showed that multi-atlas outperformed single atlas and identified an additional postprocessing step of cerebrospinal fluid removal, enhancing concordance (intraclass correlation coefficient, 0.86; DC, 0.89). CONCLUSIONS: Atlas-based parcellation performed reasonably well in the aging population. Rigorous performance assessment aided method refinement and emphasizes the importance of age matching and postprocessing. Further work is required in more varied subjects.

Full version: Available here

Click the link to go to an external website with the full version of the paper

ISBN: 1532-3145 (Electronic)0363-8715 (Linking)
Publication Year: 2013
Periodical: J Comput Assist Tomogr
Periodical Number: 2
Volume: 37
Pages: 257-64
Author Address: Brain Research Imaging Centre, Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK.