UK PET Chemistry Workshop on Radiotracer Dispensing Oct 21, 2022 09:00 AM - 05:00 PM — KCL, London
Scottish Radiotherapy Research Forum Nov 10, 2022 10:00 AM - 04:00 PM — University of Stirling
IPEM Advanced Neuro MRI Nov 15, 2022 09:00 AM - 05:00 PM — Birmingham


SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists. **Unfortunately these do not currently work in browsers**

Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Structure-activity relationships of novel iodinated quinoline-2-carboxamides for targeting the translocator protein

Author(s): A. Blair, L. Stevenson, D. Dewar, S. L. Pimlott, A. Sutherland

In an effort to develop a new SPECT imaging agent for the translocator protein (TSPO), a series of novel iodinated quinoline-2-carboxamides have been synthesised and evaluated for binding affinity using rat brain homogenates. The outcome of the biological testing in combination with HPLC determination of the physicochemical properties of these compounds directed the design of new analogues resulting in 4-(2-iodophenyl)quinoline-2-N-diethylcarboxamide, a new TSPO ligand with higher affinity than the widely used clinical imaging agent PK11195.

Full version: Available here

Click the link to go to an external website with the full version of the paper

ISBN: 2040-2503
Publication Year: 2013
Periodical: Medchemcomm
Periodical Number: 11
Volume: 4
Pages: 1461-1466
Author Address: Sutherland, A Univ Glasgow, Sch Chem, WestCHEM, Joseph Black Bldg, Glasgow G12 8QQ, Lanark, Scotland Univ Glasgow, Sch Chem, WestCHEM, Glasgow G12 8QQ, Lanark, Scotland Univ Glasgow, Coll Med Vet & Life Sci, Inst Neurosci & Psychol, Glasgow G12 8QQ, Lanark, Scotland Univ Glasgow, West Scotland Radionuclide Dispensary, Glasgow G11 6NT, Lanark, Scotland North Glasgow Univ Hosp NHS Trust, Glasgow G11 6NT, Lanark, Scotland