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eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists. **Unfortunately these do not currently work in browsers**


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

An MRI-histological study of white matter in stroke-free SHRSP

Author(s): J. F. Brittain, C. McCabe, H. Khatun, N. Kaushal, L. R. Bridges, W. M. Holmes, T. R. Barrick, D. Graham, A. F. Dominiczak, I. Mhairi Macrae, A. H. Hainsworth

Abstract:
Hypertension is associated with cerebral small vessel disease (SVD) and with diffuse white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI). We tested whether stroke-prone spontaneously hypertensive rats (SHRSP), a model of chronic hypertension, exhibit WMH. Male SHRSP (age 10 months) without stroke symptoms were compared with age-matched male WKY rats. Stroke-prone spontaneously hypertensive rats exhibited no WMH on MRI scans (T2, T2*, diffusion tensor imaging) and no neuropathological lesions. While leptomeningeal arteries exhibited fibrohyaline wall thickening, with decreased smooth muscle actin relative to WKY, deep penetrating arterioles within the caudate nuclei had no vasculopathy. We conclude that WMH are not an obligate feature of stroke-free SHRSP aged up to 10 months.

Full version: Available here

Click the link to go to an external website with the full version of the paper


ISBN: 1559-7016 (Electronic)0271-678X (Linking)
Publication Year: 2013
Periodical: J Cereb Blood Flow Metab
Periodical Number: 5
Volume: 33
Pages: 760-3
Author Address: Stroke and Dementia Research Centre, St Georges University of London, London, UK.