Through the Looking Glass: Breaking Barriers in STEM Oct 28, 2020 12:00 PM - 03:30 PM — Virtual Meeting (online)
NRS Mental Health Network Annual Scientific Meeting 2020 Nov 04, 2020 09:00 AM - 05:30 PM — Virtual Meeting (online)
Scottish Radiological Society Annual General Meeting 2020 Nov 06, 2020 09:30 AM - 03:30 PM — Virtual Meeting (online)
IPEM educational meeting: Artificial Intelligence in MRI Nov 18, 2020 12:00 AM — Virtual Meeting (online)

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Synthesis and biological evaluation of novel 2,3-dihydro-1H-1,5-benzodiazepin-2-ones; potential imaging agents of the metabotropic glutamate 2 receptor

Author(s): L. Gilfillan, A. Blair, B. J. Morris, J. A. Pratt, L. Schweiger, S. Pimlott, A. Sutherland

Abstract:
A focused library of novel 2,3-dihydro-1H-1,5-benzodiazepin-2-ones containing sites for C-11-, F-18- and I-123-labelling have been prepared and evaluated against membrane expressing human recombinant metabotropic glutamate 2 receptor (mGluR2). The compounds were found to be non-competitive antagonists with nanomolar affinity. HPLC evaluation of the physiochemical properties of these compounds identified two candidates for PET and SPECT imaging of mGluR2.

Full version: Available here

Click the link to go to an external website with the full version of the paper


ISBN: 2040-2503
Publication Year: 2013
Periodical: Medchemcomm
Periodical Number: 7
Volume: 4
Pages: 1118-1123
Author Address: Sutherland, A Univ Glasgow, Sch Chem, WestCHEM, Joseph Black Bldg, Glasgow G12 8QQ, Lanark, Scotland Univ Glasgow, Sch Chem, WestCHEM, Glasgow G12 8QQ, Lanark, Scotland Univ Glasgow, Inst Neurosci & Psychol, Glasgow G12 8QQ, Lanark, Scotland Univ Strathclyde, Strathclyde Inst Pharm & Biomed Sci, Ctr Neurosci, Glasgow G4 0RE, Lanark, Scotland Univ Aberdeen, Sch Med & Dent, John Mallard Scottish PET Ctr, Aberdeen AB25 2ZD, Scotland Univ Glasgow, West Scotland Radionuclide Dispensary, Glasgow G11 6NT, Lanark, Scotland North Glasgow Univ Hosp NHS Trust, Glasgow G11 6NT, Lanark, Scotland