Medical Imaging Convention [rescheduled] Mar 09, 2021 - Mar 10, 2021 — National Exhibition Centre, Birmingham, England
9th SINAPSE Neuro-oncology Imaging Meeting [rescheduled] Mar 11, 2021 09:30 AM - 03:30 PM — West Park Conferencing & Events, 319 Perth Road, Dundee DD2 1NN
Total Body PET 2020 conference [rescheduled] Jun 05, 2021 - Jun 07, 2021 — McEwan Hall, University of Edinburgh

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Quantitative analysis shows that contrast medium in positron emission tomography/computed tomography may cause significant artefacts

Author(s): C. McKeown, M. F. Dempsey, G. Gillen, C. Paterson

Abstract:
Objectives Attenuation correction algorithms are required for accurate quantification of PET data and for mapping of radioactive tracers. Modern PET systems incorporate computed tomography (CT) systems to perform attenuation correction. However, high-density media, such as contrast agents, may introduce potentially clinically significant artefacts in PET images when CT-based attenuation correction algorithms are used. Although various groups have investigated this issue, no study has quantitatively assessed the clinical significance of these artefacts by comparing artefact and lesion standardized uptake values (SUVs) in controlled phantom experiments. Furthermore, previous studies have focussed on the effects of increasing the concentration of contrast medium, without investigating the effects of increasing its transaxial area. This study quantifies the clinical significance of increasing the concentration and transaxial area of contrast agents and evaluates a commercially available contrast agent correction algorithm. Methods Images of a phantom containing background activity, a volume of contrast agent and varying sizes of hot lesions were acquired using clinical acquisition protocols. Quantitative analysis was performed on transaxial image slices of PET data. Results The densest medium caused a 125% SUVmean increase in the area containing, and immediately adjacent to, contrast medium when compared with a reference water phantom. As the transaxial area of the contrast medium increased, artefacts appeared as a ring of activity around the periphery of the contrast medium. The contrast correction algorithm reduced these artefacts to within 39% of the reference results. Conclusion Oral and IV contrast agents can cause clinically significant artefacts in CT-based attenuation-corrected PET images and should be used with caution. Nucl Med Commun 33:864-871 (C) 2012 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.

Full version: Available here

Click the link to go to an external website with the full version of the paper


ISBN: 0143-3636
Publication Year: 2012
Periodical: Nuclear Medicine Communications
Periodical Number: 8
Volume: 33
Pages: 864-871
Author Address: McKeown, C Gartnavel Royal Hosp, W Scotland PET Ctr, Tom Wheldon Bldg,1053 Great Western Rd, Glasgow G12 0YN, Lanark, Scotland Gartnavel Royal Hosp, W Scotland PET Ctr, Glasgow G12 0YN, Lanark, Scotland