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SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.

Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Potential effect of skull thickening on the associations between cognition and brain atrophy in ageing

Author(s): Benjamin Segun Aribisala, Natalie A. Royle, Maria C. Valdés Hernández, Catherine Murray, Lars Penke, Alan Gow, Susana Munoz-Maniega, John M. Starr, Mark Bastin, Ian Deary, Joanna Wardlaw

BACKGROUND: intracranial volume (ICV) is commonly used as a marker of premorbid brain size in neuroimaging studies as it is thought to remain fixed throughout adulthood. However, inner skull table thickening would encroach on ICV and could mask actual brain atrophy. OBJECTIVE: we investigated the effect that thickening might have on the associations between brain atrophy and cognition. METHODS: the sample comprised 57 non-demented older adults who underwent structural brain MRI at mean age 72.7 ± 0.7 years and were assessed on cognitive ability at mean age 11 and 73 years. Principal component analysis was used to derive factors of general cognitive ability (g), information processing speed and memory from the recorded cognitive ability data. The total brain tissue volume and ICV with (estimated original ICV) and without (current ICV) adjusting for the effects of inner table skull thickening were measured. General linear modelling was used to test for associations. RESULTS: all cognitive ability variables were significantly (P < 0.01) associated with percentage total brain volume in ICV measured without adjusting for skull thickening (g:

Full version: Available here

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ISBN: 0002-0729
Publication Year: 2014
Periodical: Age and Ageing
Periodical Number: 4
Volume: 43
Pages: 712-716
Author Address: