Organisation:
Department:
Keywords:
Interests:
I am an Applied Mathematician with a Physics background in non-linear dynamics and fluid dynamics. My research is centred around the analysis of complex systems, and as such, it spans broad interdisciplinary fields — including dynamical systems, network science, statistics, and data science — with applications ranging from ecosystem dynamics and neuroscience to climate forecasting and power-grids stability. Overall, my work attempts to bridge fundamental mathematical and physical theories with real-world applications, relying heavily on collaborations, mathematics, and data.
Research Themes:
I was part of a RSAT project led by Dr. V. Vuksanović (2020-2022), focused on developing a model of brain impaired functions in Alzheimer’s disease from large-scale brain networks, rather than on existing diagnostic categories. The objective of the overall project is to develop novel neuroimaging-informed ways to classify Alzheimer’s disease and mild cognitive impairment. Neuroimaging-defined connectomes will be linked to specific behavioural and cognitive scores, aiming to help in early diagnosis.
Key Publications:
- Coronel-Oliveros, C., Moguilner, S., …, Rubido, N., … & Ibanez, A. (2025). Diversity-sensitive brain clocks linked to biophysical mechanisms in aging and dementia. Nature Mental Health, 3, 1214–1229
- Anzibar Fialho, M., Martínez Barreiro, M., …, Rubido, N., A. Kun, A., & Brum, J. (2024). Functional ultrasound and brain connectivity reveal central nervous system compromise in Trembler-J mice model of Charcot-Marie-Tooth disease. Scientific Reports, 14(1), 30073
- Moguilner, S., Baez, S., Hernandez, H., … Rubido, N., … & Ibanez, A. (2024). Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations. Nature medicine, 30(12), 3646-3657
- Pascovich, C., Serantes, D., … Rubido, N., & Torterolo, P. (2024). Dorsal and median raphe neuronal firing dynamics characterized by nonlinear measures. PLoS Computational Biology, 20(5), e1012111
- Rubido, N., Riedel, G., & Vuksanović, V. (2024). Genetic basis of anatomical asymmetry and aberrant dynamic functional networks in Alzheimer’s disease. Brain Communications, 6(1), fcad320
- González, J., Cavelli, M., Tort, A. B., Torterolo, P., & Rubido, N. (2023). Sleep disrupts complex spiking dynamics in the neocortex and hippocampus. PLoS ONE, 18(8), e0290146
- González, J., Mateos, D., Cavelli, M., Mondino, A., Pascovich, C., Torterolo, P., & Rubido, N. (2022). Low frequency oscillations drive EEG’s complexity changes during wakefulness and sleep. Neuroscience, 494, 1-11
- Anzibar Fialho, M., Vázquez Alberdi, L., …, Rubido, N., Kun, A., & Brum, J. (2022). Intensity distribution segmentation in ultrafast Doppler combined with scanning laser confocal microscopy for assessing vascular changes associated with ageing in murine hippocampi. Scientific Reports, 12(1), 6784
- García, R. A., Martí, A. C., Cabeza, C., & Rubido, N. (2020). Small-worldness favours network inference in synthetic neural networks. Scientific Reports, 10(1), 2296
- González, J., Cavelli, M., Mondino, A., Pascovich, C., Castro-Zaballa, S., Torterolo, P., & Rubido, N. (2019). Decreased electrocortical temporal complexity distinguishes sleep from wakefulness. Scientific Reports, 9(1), 18457
Collaborators:
- Dr Murilo S. Baptista, University of Aberdeen, Institute for Complex Systems and Mathematical Biology, United Kingdom
- Prof Celso Grebogi, University of Aberdeen, Institute for Complex Systems and Mathematical Biology, United Kingdom
- Prof Bettina Platt, University of Aberdeen, Institute of Medical Sciences, United Kingdom
- Prof Mario Parra Rodriguez, University of Strathclyde, Psychology, United Kingdom
- Dr Melvyn Tyloo, University of Exeter, Living Systems Institute, United Kingdom
- Prof Arturo C. Martí, Universidad de la República, Nonlinear Physics group, Uruguay
- Dr Javier Brum, Universidad de la República, Laboratory of Acoustic Ultrasound, Uruguay
- Dr Pablo Torterolo, Universidad de la República, Laboratory of Sleep Neurobiology, Uruguay
- Dr Victoria Gradín, Universidad de la República, Centre for Basic Research in Psychology (CIBPsi), Uruguay
- Dr Alejandra Kun, Clemente Estable Institute for Biological Research, Uruguay
- Prof Andrés Damián, Uruguayan Centre of Molecular Imaging (CUDIM), Uruguay
- Prof Cristina Masoller, Univeristat Politecnica de Catalunya, DONLL, Barcelona, Spain