Author(s)

P. Sandercock, J. Wardlaw, R. Lindley

ISBN

1747-4930

Publication year

2010

Periodical

International Journal of Stroke

Periodical Number

5

Volume

5

Pages

381-382

Author Address

Sandercock, P Western Gen Hosp, Dept Clin Neurosci, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland Univ Edinburgh, Edinburgh, Midlothian, Scotland Univ Sydney, Sydney, NSW 2006, Australia

Full version

The publication of the updated individual patient data meta-analysis of the larger randomised trials of intravenous rt-PA for acute ischaemic stroke has re-opened the debate about how the treatment should be used in routine practice, and what information can be expected to emerge in the next 2-3 years from the ongoing trials [the largest of which is the Third International Stroke Trial (IST-3)].