Upcoming Events

ERASMUS Course on MRI: Basic MRI Physics Sep 25, 2017 - Sep 29, 2017 — Ninewells Hospital Medical School, Dundee
7th SINAPSE-SANON Meeting Sep 28, 2017 09:30 AM - 04:00 PM — Wellcome Rooms, Royal Society of Edinburgh, 22-26 George Street, Edinburgh
ECCOMAS VipIMAGE 2017 Oct 18, 2017 - Oct 20, 2017 — Porto, Portugal
ESMRMB 2017 Congress Oct 19, 2017 - Oct 21, 2017 — Fira de Barcelona, Barcelona, Spain
NRS Mental Health Network Annual Scientific Meeting Oct 25, 2017 09:00 AM - 05:00 PM — Teaching & Learning Centre, Queen Elizabeth University Hospital Glasgow

Dr William Holmes

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Position: Co-Director of Glasgow’s Experimental MRI Centre (GEMRIC), MR physicist

Interests:

I am interested in all aspects of Magnetic Resonance, with emphasis on pre-clinical research. My research interests focus on the development and application of novel MR methods in both the physical and biomedical sciences.

Institute: University of Glasgow

Department: Institute of Neuroscience & Psychology


Research Themes

Pre-clinical magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI). Development of diagnostic and therapeutic techniques in stroke. Pre-clinical therapeutic agents in oncology. Novel cardiac imaging methods. Application of MRI /MRS in the physical sciences and engineering.

Key Publications
  1. Holmes WM, Lopez-Gonzalez MR, Gallagher L, Deuchar GA, Macrae IM, Santosh C. Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR in Biomedicine. 2012. 25: 295-304.

  2. Baskerville TA, McCabe C, Mullin J, Carberry L, Macrae IM, Holmes WM. Non-invasive MRI measurement of CBF: validating an arterial spin labelling sequence with 99mTc-HMPAO CBF autoradiography in a rat stroke model. Journal of Cerebral Blood Flow and Metabolism. 2012. 32: 973-977.

  3. Ruest T, Holmes WM, Barrie JA, Griffiths IR, Anderson TJ, Dewar D , Edgar JM. High-resolution diffusion tensor imaging of fixed brain in a mouse model of Pelizaeus–Merzbacher disease: comparison with quantitative measures of white matter pathology. NMR in Biomedicine. 2011. 24: 1369-1379.

  4. Dani KA, Santosh C, Brennan D, McCabe C, Holmes WM, Condon B, Hadley DM, Macrae IM, Shaw M & Muir KW (2010).  T2* Weighted Magnetic Resonance Imaging with Hyperoxia in Acute Ischemic Stroke. Annals of Neurology. 2010. 68(1) : 37-47.

  5. Holmes WM, McCabe C, Mullin JM, Condon B, Bain MM “Non-Invasive Self-Gated MR Cardiac Imaging of Developing Chick Embryos In-Ovo.” CIRCULATION. 117, E346-347, 2008.

  6. M.R. Lopez, W.M. Holmes, P.T. Callaghan and P.J. Photinos. " Shear banding fluctuation and nematic order in wormlike micelles". Physical Reveiw Letters. 93, 268302. Dec 2004.


Collaborators

 

Prof  Mhairi Macrae,  University of Glasgow, Scotland
Prof  Keith Muir, University of Glasgow, Scotland
Prof Antony Chalmers, University of Glasgow, Scotland
Prof Barrie Condon, Scotland
Dr Chris McCabe, University of Glasgow, Scotland
Dr Martin Denvir, University of Edinburgh, Scotland
Dr Maurits Jansen, Edinburgh Univerisity, Scotland
Dr Vernon Pheonix,  University of Glasgow, Scotland
Dr Heather Haynes, Herrit Watt University, Scotland
Dr Jonathan Cox, University of Bath, England