Upcoming Events

Edinburgh Imaging PhD Expo 2018 Oct 18, 2018 01:30 PM - 06:00 PM — Room G07, Informatics Building, University of Edinburgh
PET is Wonderful Annual Meeting 2018 Oct 29, 2018 09:00 AM - 05:00 PM — South Hall Complex, Pollock Halls, University of Edinburgh
2018 NHS Research Scotland Annual Conference Oct 30, 2018 09:00 AM - 05:00 PM — Perth Concert Hall
8th SINAPSE Neuro-oncology Meeting Oct 30, 2018 09:30 AM - 04:00 PM — Royal College of Physicians and Surgeons of Glasgow, 232-242 St Vincent Street, Glasgow
Image Guided Therapies Network+ Tri-Annual Meeting Nov 01, 2018 10:00 AM - 05:00 PM — Wolfson Lecture Theatre, Ninewells Hospital, Dundee

Dr William Holmes

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Position: Co-Director of Glasgow’s Experimental MRI Centre (GEMRIC), MR physicist

Interests:

I am interested in all aspects of Magnetic Resonance, with emphasis on pre-clinical research. My research interests focus on the development and application of novel MR methods in both the physical and biomedical sciences.

Institute: University of Glasgow

Department: Institute of Neuroscience & Psychology


Research Themes

Pre-clinical magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI). Development of diagnostic and therapeutic techniques in stroke. Pre-clinical therapeutic agents in oncology. Novel cardiac imaging methods. Application of MRI /MRS in the physical sciences and engineering.

Key Publications
  1. Holmes WM, Lopez-Gonzalez MR, Gallagher L, Deuchar GA, Macrae IM, Santosh C. Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR in Biomedicine. 2012. 25: 295-304.

  2. Baskerville TA, McCabe C, Mullin J, Carberry L, Macrae IM, Holmes WM. Non-invasive MRI measurement of CBF: validating an arterial spin labelling sequence with 99mTc-HMPAO CBF autoradiography in a rat stroke model. Journal of Cerebral Blood Flow and Metabolism. 2012. 32: 973-977.

  3. Ruest T, Holmes WM, Barrie JA, Griffiths IR, Anderson TJ, Dewar D , Edgar JM. High-resolution diffusion tensor imaging of fixed brain in a mouse model of Pelizaeus–Merzbacher disease: comparison with quantitative measures of white matter pathology. NMR in Biomedicine. 2011. 24: 1369-1379.

  4. Dani KA, Santosh C, Brennan D, McCabe C, Holmes WM, Condon B, Hadley DM, Macrae IM, Shaw M & Muir KW (2010).  T2* Weighted Magnetic Resonance Imaging with Hyperoxia in Acute Ischemic Stroke. Annals of Neurology. 2010. 68(1) : 37-47.

  5. Holmes WM, McCabe C, Mullin JM, Condon B, Bain MM “Non-Invasive Self-Gated MR Cardiac Imaging of Developing Chick Embryos In-Ovo.” CIRCULATION. 117, E346-347, 2008.

  6. M.R. Lopez, W.M. Holmes, P.T. Callaghan and P.J. Photinos. " Shear banding fluctuation and nematic order in wormlike micelles". Physical Reveiw Letters. 93, 268302. Dec 2004.


Collaborators

 

Prof  Mhairi Macrae,  University of Glasgow, Scotland
Prof  Keith Muir, University of Glasgow, Scotland
Prof Antony Chalmers, University of Glasgow, Scotland
Prof Barrie Condon, Scotland
Dr Chris McCabe, University of Glasgow, Scotland
Dr Martin Denvir, University of Edinburgh, Scotland
Dr Maurits Jansen, Edinburgh Univerisity, Scotland
Dr Vernon Pheonix,  University of Glasgow, Scotland
Dr Heather Haynes, Herrit Watt University, Scotland
Dr Jonathan Cox, University of Bath, England