Upcoming Events

Molecular Imaging Workshop 2017 Nov 20, 2017 - Nov 23, 2017 — San Sebastian, Spain
TOPIM ("hot TOPics in IMaging") 2018: Imaging Metabolism Jan 21, 2018 - Jan 26, 2018 — L'Ecole de Physique des Houches, France
SINAPSE Molecular Imaging PET/SPECT focus group meeting Feb 05, 2018 10:30 AM - 04:00 PM — Carnegie Lecture Theatre (C3-05), Joseph Black Building, School of Chemistry, University of Glasgow
'Let's Talk About Health' free public lecture Feb 21, 2018 05:30 PM - 06:30 PM — Wellcome Auditorium, Queen’s Medical Research Institute, University of Edinburgh

Dr William Holmes

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Position: Co-Director of Glasgow’s Experimental MRI Centre (GEMRIC), MR physicist

Interests:

I am interested in all aspects of Magnetic Resonance, with emphasis on pre-clinical research. My research interests focus on the development and application of novel MR methods in both the physical and biomedical sciences.

Institute: University of Glasgow

Department: Institute of Neuroscience & Psychology


Research Themes

Pre-clinical magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS) and diffusion tensor imaging (DTI). Development of diagnostic and therapeutic techniques in stroke. Pre-clinical therapeutic agents in oncology. Novel cardiac imaging methods. Application of MRI /MRS in the physical sciences and engineering.

Key Publications
  1. Holmes WM, Lopez-Gonzalez MR, Gallagher L, Deuchar GA, Macrae IM, Santosh C. Novel MRI detection of the ischemic penumbra: direct assessment of metabolic integrity. NMR in Biomedicine. 2012. 25: 295-304.

  2. Baskerville TA, McCabe C, Mullin J, Carberry L, Macrae IM, Holmes WM. Non-invasive MRI measurement of CBF: validating an arterial spin labelling sequence with 99mTc-HMPAO CBF autoradiography in a rat stroke model. Journal of Cerebral Blood Flow and Metabolism. 2012. 32: 973-977.

  3. Ruest T, Holmes WM, Barrie JA, Griffiths IR, Anderson TJ, Dewar D , Edgar JM. High-resolution diffusion tensor imaging of fixed brain in a mouse model of Pelizaeus–Merzbacher disease: comparison with quantitative measures of white matter pathology. NMR in Biomedicine. 2011. 24: 1369-1379.

  4. Dani KA, Santosh C, Brennan D, McCabe C, Holmes WM, Condon B, Hadley DM, Macrae IM, Shaw M & Muir KW (2010).  T2* Weighted Magnetic Resonance Imaging with Hyperoxia in Acute Ischemic Stroke. Annals of Neurology. 2010. 68(1) : 37-47.

  5. Holmes WM, McCabe C, Mullin JM, Condon B, Bain MM “Non-Invasive Self-Gated MR Cardiac Imaging of Developing Chick Embryos In-Ovo.” CIRCULATION. 117, E346-347, 2008.

  6. M.R. Lopez, W.M. Holmes, P.T. Callaghan and P.J. Photinos. " Shear banding fluctuation and nematic order in wormlike micelles". Physical Reveiw Letters. 93, 268302. Dec 2004.


Collaborators

 

Prof  Mhairi Macrae,  University of Glasgow, Scotland
Prof  Keith Muir, University of Glasgow, Scotland
Prof Antony Chalmers, University of Glasgow, Scotland
Prof Barrie Condon, Scotland
Dr Chris McCabe, University of Glasgow, Scotland
Dr Martin Denvir, University of Edinburgh, Scotland
Dr Maurits Jansen, Edinburgh Univerisity, Scotland
Dr Vernon Pheonix,  University of Glasgow, Scotland
Dr Heather Haynes, Herrit Watt University, Scotland
Dr Jonathan Cox, University of Bath, England