PET is Wonderful Annual Meeting 2020 Oct 27, 2020 02:00 PM - 05:40 PM — Virtual Meeting (online)
Through the Looking Glass: Breaking Barriers in STEM Oct 28, 2020 12:00 PM - 03:30 PM — Virtual Meeting (online)
NRS Mental Health Network Annual Scientific Meeting 2020 Nov 04, 2020 09:00 AM - 05:30 PM — Virtual Meeting (online)
Scottish Radiological Society Annual General Meeting 2020 Nov 06, 2020 09:30 AM - 03:30 PM — Virtual Meeting (online)
IPEM educational meeting: Artificial Intelligence in MRI Nov 18, 2020 12:00 AM — Virtual Meeting (online)

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Mr Tristan Hollyer

Position: SINAPSE PhD Student
Institute: University of Glasgow
Department: Wellcome Surgical Institute


Description of Phd:

Neural stem cell therapy for stroke: A rodent based project to identify potential MRI indices of functional recovery

Stroke is leading cause of severe disability in adults. The clot-buster, Alteplase is the only licensed drug available to treat acute stroke patients however, this is only available to a small percentage of total sufferers and must be administered within the first 4.5 hours after the onset of the stoke. Although substantial research has been carried out to develop new therapies for acute brain damage and chronic disability, the translation from bench-to-bedside has proved to be a significant hurdle.

Many groups have focused on administering stem cells of patient-own or external origin to enhance brain repair. The use of  the conditionally immortalized human neural stem cell line CTX0E03 to treat sub-acute/chronic stroke is soon to enter Phase II clinical trials.

My project is an adjunct to existing pre-clinical work; aiming to understand  how the cells improve recovery using clinically applicable MRI methodologies.

I have successfully developed functional tests suitable of detecting long term functional changes post stroke. With the support of Dr Jozien Goense, we have set up resting-state fMRI in the anaesthetised rodent. With this technique at our disposal, we hope to identify indices of functional improvement in resting-state sensorimotor networks and values derived from the diffusion tensor, which may correlated with improved sensorimotor function.

This is a SPIRIT funded studentship; the stem cell technology, surgical equipment, training and a contribution of supervision for this project are supplied by industrial partner, ReNeuron ltd. (Guildford, UK).

I am a registered STEM ambassador and have participated in outreach events with EuroStemCell.