Upcoming Events

Neuroimaging in diseases that cause dementia Aug 22, 2019 - Aug 23, 2019 — King’s College Conference Centre, University of Aberdeen
2019 UK PET Chemistry Meeting Sep 09, 2019 09:00 AM - 05:45 PM — Michael Smith Building, University of Manchester
Total Body PET Workshop Sep 12, 2019 - Sep 13, 2019 — Belgian Centre for Comic Strip Art, Brussels, Belgium
Radiology events and learning from discrepancies Oct 04, 2019 09:00 AM - 05:00 PM — 200 St Vincent Street, Glasgow
IEEE International Ultrasonics Symposium 2019 Oct 06, 2019 - Oct 09, 2019 — Scottish Events Campus, Glasgow

Panos Lepipas

Position: SINAPSE PhD Student

Description of Phd:

Cyclotrons producing PET isotopes run in batch mode producing 10s of curries per run. Patient doses on the other hand tend to be a factor of 1000 smaller; i.e.; 10s of millicurries. The development of smaller isotope production units along with the utility of microfluidic technology for the radiolabelling of tracers has the potential to provide single patients doses at the push of a button. In addition cyclotrons are large and require shielding and a specialised facility for housing. A smaller isotope production unit would have the potential to be installed in any hospital site increasing the availability of PET radiotracers for imaging of patients.

Recently a small, low power table-top accelerator has been developed (Biomarker Generator, Advanced Biomarker Technologies). This ‘table top’ cyclotron is composed of an electro-magnet, a vacuum system, a radio-frequency acceleration system, a source of positive ions, a set of targets for C-11 and F-18 and a radiation shield. With shielding the total weight of the accelerator is 10.8 ton and only occupies about 2 square metres. Laser production has the potential to improve on these recent developments, requiring even less shielding. This has the potential to allow the availability of PET radiopharmaceuticals at the push of a button in any hospital site that has a PET camera. In addition the potential application of laser technology in radiotherapy may result in laser technology being marketed for dual purposes in a single system.