I am a clinical neuroradiologist carrying out research in structural, functional and molecular brain imaging correlates of cognitive ageing and dementia. Current work includes MRI in the Aberdeen 1936 Birth Cohort, and MRI, regional cerebral blood flow SPECT and FDG PET in clinical trials of novel Tau Aggregation Inhibitor therapies in Alzheimer’s disease. I am also involved in brain imaging research in neurodegenerative and neurodevelopmental diseases, utilising quantitative assessment of brain volumes, disease burden and function. I have extensive clinical experience of brain imaging in dementia, being responsible for over 500 nuclear medicine brain regional cerebral blood flow SPECT studies per annum, receptor studies in movement disorder.
Staff RT, Murray AD, Ahearn TS, Mustafa N, Fox HC, Whalley LJ. Childhood socioeconomic status and adult brain size: Childhood socioeconomic status influences adult hippocampal size. Annals of Neurology 2012; 71:653–660. Murray AD, Staff RT, McNeil CM, Salarirad S, Ahearn TA, Mustafa N, Whalley LJ. The balance of cognitive reserve and brain imaging biomarkers of cerebrovascular and Alzheimer’s diseases. Brain 2011;134(12):3684-3693. Mustafa N, Ahearn TS, Waiter GD, Murray AD, Whalley LJ, Staff RT. Brain structural complexity and life course cognitive change. NeuroImage 2012: 61; 694-701. Murray AD, Staff RT, McNeil CM, Salarirad S, Starr JM, Deary IJ, Whalley LJ. Brain lesions, hypertension and cognitive aging in the 1921 and 1936 Aberdeen birth cohorts. Age 2012; 34:451–459. Murray AD, McNeil CJ, Salarirad S, Whalley LJ, Staff RT. Early life socioeconomic circumstance and late life brain hyperintensities – a population based cohort study. PLOS ONE in press
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