Medical Imaging Convention [rescheduled] Mar 09, 2021 - Mar 10, 2021 — National Exhibition Centre, Birmingham, England
9th SINAPSE Neuro-oncology Imaging Meeting [rescheduled] Mar 11, 2021 09:30 AM - 03:30 PM — West Park Conferencing & Events, 319 Perth Road, Dundee DD2 1NN
Total Body PET 2020 conference [rescheduled] Jun 05, 2021 - Jun 07, 2021 — McEwan Hall, University of Edinburgh

eLearning

SINAPSE experts from around Scotland have developed ten online modules designed to explain medical imaging. They are freely available and are intended for non-specialists.


Edinburgh Imaging Academy at the University of Edinburgh offers the following online programmes through a virtual learning environment:

Neuroimaging for Research MSc/Dip/Cert

Imaging MSc/Dip/Cert

PET-MR Principles & Applications Cert

Applied Medical Image Analysis Cert

Online Short Courses

Publications



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3D stereophotogrammetric image superimposition onto 3D CT scan images: the future of orthognathic surgery. A pilot study

The aim of this study was to register and assess the accuracy of the superimposition method of a 3-dimensional (3D) soft tissue stereophotogrammetric image (C3D image) and a 3D image of the underlying skeletal tissue acquired by 3D spiral computerized tomography (CT). The study was conducted on a model head, in which an intact human skull was embedded with an overlying latex mask that reproduced anatomic ...

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4-chloro-N-(trimethylammonio)benzamide chloride monohydrate

The structure of the cation in the ylide hydrochloride [Me3NNHC(O)C6H4-Cl-p]Cl.H2O, or C10H14ClN2O+.Cl-.H2O, is compared with that of the free ylide. Protonation lengthens the N-C(O) bond but shortens the C=O and N-N bonds by similar to0.03 Angstrom and increases the dihedral angle between the phenyl and ylide planes.

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5-(123)I-A-85380 binding to the alpha4beta2-nicotinic receptor in mild cognitive impairment

Treatments currently licensed for Alzheimer's dementia target cholinergic brain systems. In vivo nicotinic receptor binding may provide an early marker of illness and treatment suitability. In this pilot, we examined nine patients with amnestic mild cognitive impairment (MCI) and 10 age and education matched healthy volunteers with high resolution SPECT and the nicotinic receptor ligand 5-(123)I-A-85380. ...

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5alpha-reductase type 1 modulates insulin sensitivity in men

CONTEXT: 5alpha-Reductase (5alphaR) types 1 and 2 catalyze the A-ring reduction of steroids, including androgens and glucocorticoids. 5alpha-R inhibitors lower dihydrotestosterone in benign prostatic hyperplasia; finasteride inhibits 5alphaR2, and dutasteride inhibits both 5alphaR2 and 5alphaR1. In rodents, loss of 5alphaR1 promotes fatty liver. OBJECTIVE: Our objective was to test the hypothesis that ...

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13H-Dibenzo[a,i]fluoren-13-one

Molecules of 13H-dibenzo[a,i]fluoren-13-one, C21H12O, straddle a crystallographic mirror plane and are essentially planar, with a dihedral angle of only 1.9 (1)degrees between the two naphthalene ring systems. Repulsive intramolecular C=O ... H interactions therefore do not explain the larger distortions found in isomeric ketones.

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17q25 Locus Is Associated With White Matter Hyperintensity Volume in Ischemic Stroke, But Not With Lacunar Stroke Status

Background and Purpose-Recently, a novel locus at 17q25 was associated with white matter hyperintensities (WMH) on MRI in stroke-free individuals. We aimed to replicate the association with WMH volume (WMHV) in patients with ischemic stroke. If the association acts by promoting a small vessel arteriopathy, it might be expected to also associate with lacunar stroke. Methods-We quantified WMH on MRI ...

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18F-barbiturates are PET tracers with diagnostic potential in Alzheimer's disease

Three fluoro-barbiturates were synthesised, showing in vivo sedative efficacy. One of them, [(18)F], was synthesised in radiofluorinated form. PET/CT Imaging with [(18)F] identified beta-amyloid over-expressing transgenic mice (betaA mice) compared to wild type and tau lines. The fluorescent barbiturate 9 was able to label betaA plaques in brain sections of betaA mice, and co-localise with ...

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18f-labelled barbiturate compounds for use as positron emission imaging agents

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18F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis

BACKGROUND: 18F-Sodium fluoride (18F-NaF) and 18F-fluorodeoxyglucose (18F-FDG) are promising novel biomarkers of disease activity in aortic stenosis. We compared 18F-NaF and 18F-FDG uptake with histological characterization of the aortic valve and assessed whether they predicted disease progression. METHODS AND RESULTS: Thirty patients with aortic stenosis underwent combined positron emission and computed ...

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[18F]-5-Fluoro-5-deoxyribose, an efficient peptide bioconjugation ligand for positron emission tomography (PET) imaging

[18F]-5-Fluoro-5-deoxyribose ([18F]-FDR) conjugates much more rapidly than [18F]-FDG under mild reaction conditions to peptides and offers new prospects for mild and rapid bioconjugation for fluorine-18 labelling in PET imaging.

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