May 2025: Commentary in the Brain Communications journal highlights study on fatigue in early multiple sclerosis.
A recent study led by SINAPSE members Dr Rozanna Meijboom, Dr Peter Foley and Professor Adam Waldman, “Fatigue in early multiple sclerosis: MRI metrics of neuroinflammation, relapse and neurodegeneration” (Meijboom et al. 2024), has been the focus of a commentary by Professor Lauren Krupp, published in Brain Communications.
Professor Krupp is an internationally recognised leader in fatigue and multiple sclerosis (MS). In the commentary, she highlights the importance of the study’s findings in advancing efforts to understand MS-related fatigue—one of the most common yet complex symptoms of the disease.
In their study, Dr Rozanna Meijboom and colleagues present findings from the large, longitudinal, multi-centre FutureMS study, led by the Anne Rowling Clinic. Their results show that, in individuals newly diagnosed with MS, fatigue cannot be readily explained by structural imaging measures of inflammation or neurodegeneration.
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