Dr Cassandra Sampaio Baptista

cassandra.sampaiobaptista@glasgow.ac.uk

Organisation:

Institute of Neuroscience and Psychology, University of Glasgow

Department:

MVLS

Homepage:

https://www.win.ox.ac.uk/people/cassandra-sampaiobaptista

Keywords:

DTI-tractography, Diffusion imaging, Functional Connectivity, Functional MRI (fMRI), Magnetization transfer, MRS, Preclinical Imaging, Stroke, Structural imaging, White matter disease

Interests:

My research focuses on functional and structural plasticity with learning and rehabilitation in both humans and rodents.
I use behavioural training interventions and test how factors such as performance level or amount of practice influence brain changes at a functional, structural and neurochemical level in humans (fMRI, rs-fMRI, DTI and MR spectroscopy).
Additionally, I use real-time neurofeedback fMRI to test if endogenous brain activity modulation can lead to functional brain changes and behavioural improvements in healthy participants and chronic stroke survivors.
My preclinical work focuses on the underlying cellular mechanisms of brain plasticity, with a focus on white matter and myelination.

Key Publications:

Sampaio-Baptista C*, Valles A*, Martens G, De Weerd P and Johansen-Berg H. Experience-related alterations in white matter structure and gene expression in adult rats. Progress in Neurobiology, 101770. * Shared first author

Sampaio-Baptista C, Sanders ZB, Johansen-Berg H. (2018). Structural Plasticity in Adulthood with Motor Learning and Stroke Rehabilitation. Annual Review of Neuroscience. doi.org/10.1146/annurev- neuro-080317-062015.

Sampaio-Baptista C and Johansen-Berg H. (2017). White Matter Plasticity In The Adult Brain. Neuron 96 (6), 1239-1251

Sampaio-Baptista C, Fillipini N, Stagg CJ, Near J , Scholz J and Johansen-Berg H. (2015). Changes in functional connectivity and GABA concentration with long-term motor learning. Neuroimage. 106, 15-20.

Sampaio-Baptista C , Scholz J, Jenkinson M, Thomas AG , Smit, Nicola Filippini, Gwenalle Douaud and Johansen-Berg H. (2014). Grey Matter Volume Is Associated With Rate Of Subsequent Skill Learning After A Long Term Training Intervention. Neuroimage. 96, 158-166.

Sampaio-Baptista C, Schlagheck T, Khrapichev A, Foxley S, Scholz J, Jbabdi S, De Luca G, Miller K, Taylor A, Thomas N, Kleim J, Sibson N, Bannerman D and Johansen-Berg H. (2013). Motor skill learning induces changes in white matter microstructure and myelination. The Journal of Neuroscience. 33, 19499-19503.