My research is mainly focused on investigating the cognitive and neural correlates of a range of neuropsychiatric symptoms (e.g., delusions, sleep disorder, depression, apathy).
I am interested in improving the diagnosis/detection of Alzheimer’s disease and other types of dementia (especially in the earliest stages) through customised assessment methods or through the use of multivariate markers. Variants of these markers could also be used to stratify patients or as outcome measures for clinical drug trials. Relatedly, I have interests in developing methods to speed drug development.
I have projects underway to develop serum blood-based biomarkers for the dementias (in combination with other methods), to investigate the diagnostic utility of customised neuropsychological tests (and analysis methods), and in the near future hope to begin a project that will utilise electrophysiological methods.
I have an additional research line that focuses on understanding the neural bases of hypnosis and suggestibility. By targeting individual differences suggestion can be used to study elements of psychosis, changes in agency, and other interesting psychological and behavioural phenomena.
Within my research I use structural magnetic resonance imaging techniques (voxel-based morphometry and cortical thickness assessment), functional magnetic resonance imaging (brain activity and connectivity analyses), electrophysiological methods, and neuropsychological assessment.