D. Sheppard, L. Allan, P. Martin, T. McLeay, W. Milne, J. G. Houston
Journal of Magnetic Resonance Imaging
Sheppard, D Portiuncula Hosp, Dept Clin Radiol, Galway, Ireland Tayside Univ Hosp NHS Trust, Ninewells Hosp, Dept Clin Radiol, Dundee, Scotland
Mangafodipir, a manganese-containing hepatobiliary contrast agent, is excreted in bile. We review the principles and practice of a contrast-enhanced MRC technique using mangafodipir and compare it with standard T2-weighted magnetic resonance cholangiography (MRC) sequences. Potential applications include the evaluation of leaks and strictures; the assessment of drainage in normal, surgically by-passed, stented and obstructed biliary systems; the diagnosis of cholecystitis; and the evaluation of normal and variant biliary anatomy.