Insular cortex hypoperfusion and acute phase blood glucose after stroke – A CT perfusion study

Background and Purpose-Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke. Methods-We retrospectively analyzed insular perfusion on perfusion CT (median 180 minutes after onset) in 35 patients. Results-We found no association of hypoperfusion (relative cerebral blood flow < 0.51) with early (< 6 hours) or delayed (< 72 hours) hyperglycemia, or hemispheric lateralization. Conclusions-Insular cortex hypoperfusion < 6 hours after stroke onset was not associated with hyperglycemia. ( Stroke. 2007; 38:407-410.)