We describe a positive influence of pre-stroke surgery on recovery and survival in a commonly used experimental stroke model. Two groups of male, stroke-prone spontaneously hypertensive rats (SHRSPs) underwent transient …more
The observation of blood oxygenation level-dependent (BOLD) effect in functional magnetic resonance imaging (fMRI) studies is often hampered by the presence of magnetic field in homogeneities. These are caused by …more
Aims: The aim of this review is to consolidate our knowledge on an important and rapidly expanding area of expertise. Numerous methods for predicting response (in terms of pathological response …more
PET imaging with 18F-fluorodeoxyglucose (FDG) has become a valuable procedure in oncology patient management and drug development. The availability of non-FDG radiotracers to study different aspects of cancer biology presents …more
Purpose: To determine whether [F-18]-fluorodeoxy-D-glucose ([F-18]-FDG) positron emission tomography (PET) can predict the pathologic response of primary and metastatic breast cancer to chemotherapy. Patients and Methods: Thirty patients with noninflammatory, …more
Background: Most empirically derived antidepressants increase monoamine levels. The nuclei of cells synthesising these monoamines are located in the brainstem, and projection tracts such as the medial forebrain bundle reach …more
Numerous areas of chemistry can benefit from the ongoing genomic revolution. Here, we discuss and highlight trends in chemistry in the postgenomic era. The areas of interest include combinatorial approaches …more
Background and Purpose-Lacunar ischemic stroke accounts for 25% of all ischemic strokes, but the exact etiology is unknown. Numerous pathophysiologies have been proposed, including atheroma and endothelial dysfunction. Models of …more
BACKGROUND: intracranial volume (ICV) is commonly used as a marker of premorbid brain size in neuroimaging studies as it is thought to remain fixed throughout adulthood. However, inner skull table …more
The Lenz effect on the motion of metal containing moving parts of artificial heart valves has not been considered to date. In this paper the basic theory is outlined and …more
We describe a novel magnetic resonance imaging technique for detecting metabolism indirectly through changes in oxyhemoglobin: deoxyhemoglobin ratios and T2* signal change during ‘oxygen challenge’ (OC, 5 mins 100% O-2). …more
Background and Purpose – We sought to perform a large, prospective, multicenter, blinded study comparing power transcranial color duplex sonography (power TCDS) with intra-arterial digital subtraction angiography (IADSA) in the …more
Background and Purpose-The extent of variation in the interventional treatment of brain arteriovenous malformations (AVMs) is unknown, so we explored patterns of treatment at 4 neuroscience centers in one European …more
We describe the case of a 56-year-old woman who suffered vivid visual hallucination following subarachnoid haemorrhage (SAH). These occurred from day 9 to day 28 after the haemorrhage. An association …more
Perfusion-diffusion (perfusion-weighted imaging (PWI)/diffusion-weighted imaging (DWI)) mismatch is used to identify penumbra in acute stroke. However, limitations in penumbra detection with mismatch are recognized, with a lack of consensus on …more