Lacunar infarction is associated with distinct clinical features. It is thought to result from occlusion of a deep perforating artery in the basal ganglia, centrum sentiovale, or brain stem. However, …more

PURPOSE: To distinguish between contributions to dementia made by homocysteine, folate, B12 and antioxidant micronutrients. METHODS: This is a follow-up study of a sample reported in 2002. Homocysteine was measured …more

Objectives-The accuracy of magnetic resonance angiography (MRA) was determined in patients with recently symptomatic tight (80%-99%) carotid stenosis (on Doppler ultrasound), and the effect of stenosis severity on the accuracy …more

Intracerebral haemorrhage may be visible indefinitely on MRI, due to persistence of haemosiderin in macrophages around the lesion, but it is not clear whether all haemorrhages produce haemosiderin or, if …more

OBJECTIVES: To describe the discovery and development of the Aberdeen 1921 and 1936 birth cohort studies. STUDY DESIGN: The Aberdeen birth cohort studies were started in 1998 when the Scottish …more

EEG and MEG have excellent temporal resolution, but the estimation of the neural sources that generate the signals recorded by the sensors is a difficult, ill-posed problem. The high spatial …more

Objectives-The Oxfordshire Community Stroke Project (OCSP) classification is a simple clinical scheme for subdividing first ever acute stroke. Several small studies have shown that when an infarct is visible on …more